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Interactions Between Depressive Symptoms, Childhood Trauma, and Drug Craving in Chinese Men with Methamphetamine Use Disorder

A Network Analysis

Bibliographic Data

ID13912972
AuthorsDeyang Li (0000-0002-3670-4590, Chinese Academy of Sciences), Dongmei Wang (0000-0001-6900-8295, Chinese Academy of Sciences, corresponding author), Yang Tian (0000-0001-6407-5608, Chinese Academy of Sciences), Z Chang (0009-0008-5272-0364, Columbia University), Jiajing Chen (0000-0003-0523-4132, Chinese Academy of Sciences), Lianglun Jia (Xin Hua Drug Rehabilitation Center), Fabing Fu (Xin Hua Drug Rehabilitation Center), Xiaotao Wang (0000-0003-4543-5270, Xin Hua Drug Rehabilitation Center), Xiangyang Zhang (0000-0003-3326-382X, Chinese Academy of Sciences, corresponding author), Xiang-Yang Zhang (Chinese Academy of Sciences)
Year2025
Pages1-11
Publication date2025-03-05
Peer ReviewedYes
Open AccessNo
TypeARTICLE
VenueJournal of Psychoactive Drugs (JOURNAL)
Journal identifiersISSN: 0279-1072 • E-ISSN: 2159-9777
PublisherTaylor & Francis (PUBLISHER • GB)
DOI10.1080/02791072.2025.2474747
PMID40041981
OpenAlexW4408245752
LanguageEN
Citations received1
References cited66

Drug craving in methamphetamine use disorder (MAUD) patients is influenced by various adverse psychological problems. This study adopted network analysis to investigate the interrelationships between psychological correlates and drug craving and identify the critical pathways between them. A total of 757 men with MAUD were recruited from a drug rehabilitation center in southwest China. They completed self-report scales to measure emotion regulation, depressive symptoms, childhood trauma, and drug craving. We conducted a network analysis to assess the interaction between psychological variables and drug craving. Network structural features included network centrality, stability, and bridge strength. Results revealed positive correlations between various psychological correlates and drug craving. Limited access to emotion regulation strategies, lack of emotional awareness, and non-acceptance of emotional responses emerged as the nodes with the highest strength centrality. A bridge function analysis identified that depressive symptoms, emotional abuse, and negative reinforcement were the main bridges connecting psychological problems and drug craving. These findings support the interaction between affective factors, childhood traumatic experiences, and drug craving. Central symptoms (e.g. limited access to emotion regulation strategies) and key bridge symptoms (e.g. depressive symptoms) may serve as potential targets for intervention for MAUD patients undergoing withdrawal treatment

Addiction · Craving · Drug · Methamphetamine · Psychiatry · Substance abuse · Child and Adolescent Psychosocial and Emotional Development · Clinical Psychology · Medicine · Mental Health Research Topics · Psychology · Schizophrenia research and treatment

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Unique citing works1
Citations per year1
Citation span2026 - 2026 (1)
Citation velocitycurrent
Highly citedNo
Citation typesNeutral: 1

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