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The Blue Lotus Flower ( Nymphea caerulea ) Resin Used in a New Type of Electronic Cigarette, the Re-Buildable Dripping Atomizer

Bibliographic Data

ID13914506
AuthorsJustin L Poklis (0000-0001-5470-5717, Virginia Commonwealth University, corresponding author), Haley A Mulder (0000-0003-1480-5240, Virginia Commonwealth University), Matthew S Halquist (0000-0001-9591-3117, Virginia Commonwealth University), Carl E Wolf (0009-0001-5249-2532, Assistant Professor, Departments of Pathology and Forensic Science, Virginia Commonwealth University, Richmond, VA, USA), Alphonse Poklis (Professor, Departments of Pathology, Pharmacology and Toxicology and Forensic Science, Virginia Commonwealth University, Richmond, VA, USA), Michelle R Peace (0000-0002-1480-139X, Virginia Commonwealth University)
Year2017
Volume49
Issue3
Pages175-181
Publication date2017-03-07
Open AccessNo
TypeARTICLE
VenueJournal of Psychoactive Drugs (JOURNAL)
Journal identifiersISSN: 0279-1072 • E-ISSN: 2159-9777
PublisherTaylor & Francis (PUBLISHER • GB)
DOI10.1080/02791072.2017.1290304
PMID28266899
OpenAlexW2592839781
LanguageEN
Citations received3
References cited13

The blue lotus flower (Nymphea caerulea) is an Egyptian water lily containing apomorphine and nuciferine. Apomorphine has been described as a psychoactive alkaloid and is a non-selective dopamine agonist primarily used to treat Parkinson's disease as it stimulates dopamine receptors and improves motor function. Nuciferine is an alkaloid associated with dopamine receptor blockade. Today, blue lotus flower is used as a sleep aid and anxiety reliever. The rebuildable dripping atomizer (RDA) is an electronic cigarette that allows direct application of an e-liquid onto the coil in the atomizer for aerosolization, compared to a typical electronic cigarette where the e-liquid is wicked from a storage vessel to the coil. Our laboratory received a dark-brown resin material from a concerned parent. The resin had been confiscated from an adolescent who had a reported history of marijuana use. The resin was later identified as blue lotus flower (N. caerulea). This resin, together with four commercially available blue lotus products, was analyzed for content. Apomorphine was detected in two samples, and nuciferine was detected in all five samples. The confiscated resin was determined to contain no apomorphine and 4300 ng/g of nuciferine. The nuciferine resin was shown to aerosolize using aRDA electric cigarette

Agonist · Alkaloid · Apomorphine · Biology · Botany · Dopamine · Dopamine agonist · Lotus · Lotus effect · Receptor · Analytical Chemistry and Chromatography · Chemistry · Chromatography in Natural Products · Medicine · Neurotransmitter Receptor Influence on Behavior · Biochemistry · Internal Medicine · Organic Chemistry

  • Survey of U.S. Residents and Their Usage of Electronic Cigarettes with Drugs Other Than Nicotine

    Alaina K Holt, Alyssa K Rudy et al.•Journal of Psychoactive Drugs•2023

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    Open Access•Monique Williams, Prue Talbot•International Journal of…•2019

  • Automated dripping devices for vapers

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  • The Sacred Journey in Dynastic Egypt

    William A Emboden, William Emboden•Journal of Psychoactive Drugs•1989

Citations per year0.33
Citation span2017 - 2023 (7)
Highly citedNo

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