Population differences in allele frequencies at the OLR1 locus may suggest geographic disparities in cardiovascular risk events

Bibliographic Data

ID13924318
AuthorsIrene M Predazzi (University of Rome Tor Vergata, corresponding author), Cristina Martinez‐labarga (0000-0003-0439-0379, University of Rome Tor Vergata), Cristina Martinez-Labarga, Lucia Vecchione (0000-0002-7984-6871), Ruggiero Mango, Cinzia Ciccacci (0000-0002-3995-7032), Francesca Amati (0000-0003-2209-2156), Claudio Ottoni (0000-0001-8870-1589, University of Rome Tor Vergata), M H Crawford (0000-0001-7103-2278, University of Kansas), Olga Rickards (0000-0003-2880-7466, University of Rome Tor Vergata), Francesco Romeo (0000-0003-1706-3473), Giuseppe Novelli (0000-0002-7781-602X)
Year2009
Volume37
Issue2
Pages137-149
Publication date2009-12-06
Peer ReviewedYes
Open AccessYes
TypeARTICLE
VenueAnnals of Human Biology (JOURNAL)
Journal identifiersISSN: 0301-4460 • E-ISSN: 1464-5033
PublisherInforma (PUBLISHER • GB)
DOI10.3109/03014460903393857
PMID19961348
OpenAlexW2125136369
LanguageEN
References cited44

The results confirm significant genetic structuring among populations and suggest a possible basis for varying susceptibility to CVD among groups correlated with the geographical location of populations linked with the migrations out of Africa, or with different lifestyle

Allele · Allele frequency · Biology · Coronary artery disease · Disease · Environmental health · Evolutionary biology · Gene · Locus (genetics · Population · Adipokines, Inflammation, and Metabolic Diseases · Atherosclerosis and Cardiovascular Diseases · Cholesterol and Lipid Metabolism · Demography · Medicine · Genetics · Internal Medicine

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