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Effort-based decision making in psychopathology

A transdiagnostic multilevel meta-analysis and systematic review of behavioral patterns and mechanisms underlying amotivational psychopathology

Bibliographic Data

ID14446126
AuthorsMatthias Pillny (0000-0003-2395-8433, Universität Hamburg), Katharina E Renz (0000-0003-2406-4255, Universität Hamburg), Alina Hay (Universität Hamburg), Daniel Fulford (0000-0003-4405-9031, Boston University), Tania M Lincoln (0000-0002-6674-2440, Universität Hamburg), Deanna M Barch (0000-0003-1693-8506, Washington University in St. Louis), James M Gold (0000-0002-0109-9554, University of Maryland, Baltimore), Stefan Kaiser (0000-0002-3013-2034, Geneva College)
Year2026
Volume152
Issue1
Pages33-65
Publication date2026-03-05
Open AccessYes
TypeARTICLE
VenuePsychological Bulletin (JOURNAL)
Journal identifiersISSN: 0033-2909 • E-ISSN: 1939-1455
PublisherAmerican Psychological Association (APA) (PUBLISHER)
DOI10.1037/bul0000510
PMID41785146
OpenAlexW7133865312
LanguageEN

0.01). Altered effort allocation patterns were marked by reduced effort exertion across increasing reward and probability conditions, with schizophrenia spectrum disorders showing the most pronounced deficits. The most robust moderators were the number of probability conditions, ethnicity, gender, and the severity of positive and negative symptoms. A narrative synthesis of computational modeling studies indicated that maladaptive EBDM may reflect increased effort sensitivity, reduced reward sensitivity, and cognitive impairment, with variations across disorders. Whereas schizophrenia spectrum disorders are associated with unsystematic effort allocation and cognitive deficits, major depressive disorder and bipolar disorder show heightened effort sensitivity. Overall, findings point to both shared and disorder-specific mechanisms of EBDM, offering directions for targeted interventions. (PsycInfo Database Record (c) 2026 APA, all rights reserved)

Cognition · MEDLINE · Multilevel model · Research Domain Criteria · Anxiety, Depression, Psychometrics, Treatment, Cognitive Processes · Obsessive-Compulsive Spectrum Disorders · Personality Disorders and Psychopathology

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