The Nonmedical Use of Ketamlne, Part Two
A Review of Problent Use and Dependence
Bibliographic Data
| ID | 14675989 |
|---|---|
| Authors | Karl Jansen (0000-0002-1574-7591, St Thomas' Hospital), Karl L R Jansen, Rachael Darracot-Cankovic (Open Rights Group) |
| Year | 2001 |
| Volume | 33 |
| Issue | 2 |
| Pages | 151-158 |
| Publication date | 2001-06-01 |
| Open Access | No |
| Type | ARTICLE |
| Venue | Journal of Psychoactive Drugs (JOURNAL) |
| Journal identifiers | ISSN: 0279-1072 • E-ISSN: 2159-9777 |
| Publisher | Informa UK Limited (PUBLISHER • GB) |
| DOI | 10.1080/02791072.2001.10400480 |
| PMID | 11476262 |
| OpenAlex | W2148291000 |
| Language | EN |
| Citations received | 4 |
| References cited | 42 |
This is the second part of a review of the nonmedical use of ketamine. Part one discussed the history of ketamine, the sought-after effects for which it is taken in a nonmedical context, how these are produced, common adverse effects, the ketamine schizophrenia model and the neurotoxicity issue. Part two reviews what is currently known about problem use of ketamine, ketamine dependence, treatment options and harm minimization issues. Some ketamine users become dependent on the drug in a manner resembling cocaine dependence, with craving and a high tolerance but no evidence of a physiological withdrawal syndrome. The likely mechanisms of this dependence are discussed in terms of what is known about the neurochemistry of ketamine, its psychological effects, and published case histories in both the formal and informal literature. The conclusions are that ketamine dependence is linked with effects that this complex drug has in common with not only cocaine and amphetamine but also with opiates, alcohol and cannabis, as well as the psychological attractions of its distinctive psychedelic properties
Addiction · Amphetamine · Cannabis · Cannabis Dependence · Craving · Drug · Hallucinogen · Ketamine · Neurochemistry · Psychiatry · Cannabis and Cannabinoid Research · Clinical Psychology · Medicine · Neuroscience · Neurotransmitter Receptor Influence on Behavior · Psychedelics and Drug Studies · Psychology · Neurology
| Citations per year | 0.18 |
|---|---|
| Citation span | 2004 - 2017 (14) |
| Highly cited | No |