Strategies for the prevention of hereditary diseases in a highly consanguineous population
Bibliographic Data
| ID | 14679657 |
|---|---|
| Authors | Brian F Meyer (0000-0002-0388-9568, King Faisal Specialist Hospital & Research Centre, corresponding author) |
| Year | 2005 |
| Volume | 32 |
| Issue | 2 |
| Pages | 174-179 |
| Publication date | 2005-03-01 |
| Peer Reviewed | Yes |
| Open Access | Yes |
| Type | ARTICLE |
| Venue | Annals of Human Biology (JOURNAL) |
| Journal identifiers | ISSN: 0301-4460 • E-ISSN: 1464-5033 |
| Publisher | Informa UK Limited (PUBLISHER • GB) |
| DOI | 10.1080/03014460500075217 |
| PMID | 16096214 |
| OpenAlex | W2044454094 |
| Language | EN |
| Citations received | 5 |
| References cited | 11 |
Autosomal recessive hereditary diseases are relatively common in the Saudi population. The consanguinity rate is in excess of 50% and is a practice that remains strongly embedded within Saudi culture. The impact of this practice is recognized and is being addressed. Early detection and treatment of diseases can reduce mortality and minimize morbidity. This is the basis of successful neonatal screening for inborn errors of metabolism where treatment or modification of lifestyle can modulate disease. Ultimately, understanding the genetics of these diseases will provide opportunities for prevention. Options such as prenatal screening can be used to reduce the incidence of live births with inherited diseases. However, prenatal diagnosis and associated intervention is unacceptable to wide sections of all societies. Carrier detection and genetic counselling programmes have been very successful in reducing the incidence of inherited disorders in many populations. These programmes are most successful when they are sensitive to the cultural backgrounds of populations in which they are applied. In Saudi society, premarital screening to identify carrier status and the provision of appropriate counselling has tremendous potential to prevent inherited disease
Biology · Consanguinity · Disease · Environmental health · Fetus · Genetic counseling · Hereditary Diseases · Newborn screening · Pathology · Population · Pregnancy · Prenatal diagnosis · Psychiatry · Folate and B Vitamins Research · Genomics and Rare Diseases · Medicine · Metabolism and Genetic Disorders · Genetics · Pediatrics
Effects of a Formal Training Programme on Consanguineous Marriages on High School Students' Knowledge and Attitudes
Consanguineous marriages
Knowledge and Perception of and Attitude toward a Premarital Screening Program in Qatar
Health beliefs of unmarried adult Saudi individuals toward safe marriage and the role of premarital screening in avoiding consanguinity
Autism in Saudi Arabia
| Unique citing works | 5 |
|---|---|
| Citations per year | 0,29 |
| Citation span | 2009 - 2024 (16) |
| Citation velocity | recent |
| Highly cited | No |
| Citation types | Neutral: 4 |