Hepatoprotective action mechanism and quantification of soyasaponin Bb in Abri Herba by HPLC and network pharmacology
Bibliographic Data
| ID | 14726884 |
|---|---|
| Authors | Xingmei Lin (Fujian University of Traditional Chinese Medicine), Chengzhong Zhang (0000-0002-8199-6836), Cheng‐Zhong Zhang (0000-0001-8825-7158), Baokang Huang (0000-0003-0045-5489, Fujian University of Traditional Chinese Medicine, corresponding author) |
| Year | 2025 |
| Volume | 337 |
| Issue | Pt 2 |
| Pages | 118850 |
| Publication date | 2025-01-01 |
| Open Access | Yes |
| Type | ARTICLE |
| Venue | Journal of Ethnopharmacology (JOURNAL) |
| Journal identifiers | ISSN: 0378-8741 • E-ISSN: 1872-7573 |
| Publisher | Elsevier BV (PUBLISHER) |
| DOI | 10.1016/j.jep.2024.118850 |
| PMID | 39322020 |
| OpenAlex | W4402734993 |
| Language | EN |
| References cited | 11 |
Soyasaponin Bb is primarily distributed in the root of AC, and it has a strong protective effect against CCl 4 -induced acute liver injury. It can reduce the level of inflammatory factors, relieve inflammation, and exert anti-fibrotic activity by regulating the TGF-β 1 /α-SMA pathway. Its potential anti-hepatic fibrosis mechanism has been investigated through network pharmacology
Action (physics · Biological activity · Chromatography · Epistemology · High-performance liquid chromatography · In vitro · Mechanism (biology · Mechanism of Action · Pharmacognosy · Traditional medicine · Chemistry · Ethnobotanical and Medicinal Plants Studies · Medicine · Natural Antidiabetic Agents Studies · Philosophy · Phytochemistry and biological activities of Ficus species · Biochemistry · Pharmacology
| Highly cited | No |
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