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Integrated network pharmacology and metabolomics to explore the mechanism of Kadsura coccinea root in alleviating acetaminophen-induced liver injury

Datos Bibliográficos

ID14727005
AutoresYa-shi Wang (Hunan University of Traditional Chinese Medicine), Shiqi Liu (0000-0003-1443-2675, Hunan University of Traditional Chinese Medicine), Shi-qi Liu, Yu-xuan Yao (Hunan University of Traditional Chinese Medicine), Shuo Zhang (0000-0002-7812-4260, Hunan University of Traditional Chinese Medicine), Dong-Hui Li (Hunan University of Traditional Chinese Medicine), Huiying Li (0000-0001-5633-5270, Hunan University of Traditional Chinese Medicine), Hui-ying Li, Huang-he Yu, Huanghe Yu (Hunan University of Traditional Chinese Medicine), Han-wen Yuan, Hanwen Yuan (0000-0002-2288-7656, Hunan University of Traditional Chinese Medicine), Wei Wang (0000-0001-5806-2368, Hunan University of Traditional Chinese Medicine, autor de correspondencia), Bin Li (0000-0002-9633-0033, Hunan University of Traditional Chinese Medicine, autor de correspondencia), Yu-pei Yang, Yupei Yang (0000-0002-1436-4775, Hunan University of Traditional Chinese Medicine, autor de correspondencia)
Año2025
Volumen352
Páginas120278
Fecha de publicación2025-08-01
Peer ReviewedSí
Open AccessSí
TipoARTICLE
RevistaJournal of Ethnopharmacology (JOURNAL)
Identificadores de la revistaISSN: 0378-8741 • E-ISSN: 1872-7573
EditorialElsevier BV (PUBLISHER)
DOI10.1016/j.jep.2025.120278
PMID40651730
OpenAlexW4412392836
IdiomaEN
Referencias citadas49

Biology · Enzyme · Gene · Gene expression · Gene ontology · Glutathione · Hepatoprotection · KEGG · Liver injury · Traditional medicine · Drug-Induced Hepatotoxicity and Protection · Medicine · Metabolomics and Mass Spectrometry Studies · Pharmacogenetics and Drug Metabolism · Biochemistry · Pharmacology

  • Analgesic and anti-inflammatory effects and molecular mechanisms of Kadsura heteroclita stems, an anti-arthritic Chinese Tujia ethnomedicinal herb

    Open Access•Huang-he Yu, Huanghe Yu et al.•Journal of Ethnopharmacology•2019

  • An herbal formulation “Shugan Xiaozhi decoction” ameliorates methionine/choline deficiency-induced nonalcoholic steatohepatitis through regulating inflammation and apoptosis-related pathways

    Open Access•Shuai Wang, Bohao Chen et al.•Journal of Ethnopharmacology•2024

  • Network pharmacology and experimental validation of effects of total saponins extracted from Abrus cantoniensis Hance on acetaminophen-induced liver injury

    Open Access•Jiali He, LePing Chen et al.•Journal of Ethnopharmacology•2024

  • Integrating UPLC-Q-Exactive Orbitrap/MS, Network pharmacology and experimental validation to reveal the potential mechanism of Kadsura coccinea roots in Colon Cancer

    Open Access•Shiqi Liu, Shi-qi Liu et al.•Journal of Ethnopharmacology•2025

  • Network pharmacology combines machine learning, molecular simulation dynamics and experimental validation to explore the mechanism of acetylbinankadsurin A in the treatment of liver fibrosis

    Open Access•Wangxia Peng, Yupei Yang et al.•Journal of Ethnopharmacology•2024

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