(R)-hydroxytabernaelegantine C
A bisindole alkaloid with potent apoptosis inducing activity in colon (HCT116, SW620) and liver (HepG2) cancer cells
Bibliographic Data
| ID | 14727429 |
|---|---|
| Authors | Angela Paterna (0000-0002-4903-4143, University of Lisbon), Sofia E Gomes (0000-0003-3624-1933, University of Lisbon), Pedro M Borralho (0000-0003-4488-7240, University of Lisbon), Silva Mulhovo (Pedagogical University), Cecília M P Rodrigues (0000-0002-4829-754X, University of Lisbon), Maria-José U Ferreira, Maria‐José U Ferreira (0000-0002-8742-1486, University of Lisbon, corresponding author) |
| Year | 2016 |
| Volume | 194 |
| Pages | 236-244 |
| Publication date | 2016-12-01 |
| Peer Reviewed | Yes |
| Open Access | Yes |
| Type | ARTICLE |
| Venue | Journal of Ethnopharmacology (JOURNAL) |
| Journal identifiers | ISSN: 0378-8741 • E-ISSN: 1872-7573 |
| Publisher | Elsevier BV (PUBLISHER) |
| DOI | 10.1016/j.jep.2016.09.020 |
| PMID | 27616029 |
| OpenAlex | W2519423640 |
| Language | EN |
| References cited | 32 |
Alkaloid · Apocynaceae · Apoptosis · Biology · Botany · Enzyme · Flow cytometry · IC50 · In vitro · Lactate dehydrogenase · Stereochemistry · Viability assay · Alkaloids: synthesis and pharmacology · Berberine and alkaloids research · Chemistry · Phytochemical Studies and Bioactivities · Biochemistry · Molecular Biology · Pharmacology
Apoptosis
Natural Products as Sources of New Drugs over the Last 25 Years
Cancer incidence and mortality worldwide
Natural Products As Sources of New Drugs over the 30 Years from 1981 to 2010
Plants as a source of anti-cancer agents
Monoterpene bisindole alkaloids, from the African medicinal plant Tabernaemontana elegans, induce apoptosis in HCT116 human colon carcinoma cells
| Citation velocity | historical |
|---|---|
| Highly cited | No |