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(R)-hydroxytabernaelegantine C

A bisindole alkaloid with potent apoptosis inducing activity in colon (HCT116, SW620) and liver (HepG2) cancer cells

Bibliographic Data

ID14727429
AuthorsAngela Paterna (0000-0002-4903-4143, University of Lisbon), Sofia E Gomes (0000-0003-3624-1933, University of Lisbon), Pedro M Borralho (0000-0003-4488-7240, University of Lisbon), Silva Mulhovo (Pedagogical University), Cecília M P Rodrigues (0000-0002-4829-754X, University of Lisbon), Maria-José U Ferreira, Maria‐José U Ferreira (0000-0002-8742-1486, University of Lisbon, corresponding author)
Year2016
Volume194
Pages236-244
Publication date2016-12-01
Peer ReviewedYes
Open AccessYes
TypeARTICLE
VenueJournal of Ethnopharmacology (JOURNAL)
Journal identifiersISSN: 0378-8741 • E-ISSN: 1872-7573
PublisherElsevier BV (PUBLISHER)
DOI10.1016/j.jep.2016.09.020
PMID27616029
OpenAlexW2519423640
LanguageEN
References cited32

Alkaloid · Apocynaceae · Apoptosis · Biology · Botany · Enzyme · Flow cytometry · IC50 · In vitro · Lactate dehydrogenase · Stereochemistry · Viability assay · Alkaloids: synthesis and pharmacology · Berberine and alkaloids research · Chemistry · Phytochemical Studies and Bioactivities · Biochemistry · Molecular Biology · Pharmacology

  • Apoptosis

    Open Access•Susan Elmore, Susan A Elmore•Toxicologic Pathology•2007

  • Natural Products as Sources of New Drugs over the Last 25 Years

    David J Newman, Gordon M Cragg•Journal of natural products•2007

  • Cancer incidence and mortality worldwide

    Open Access•J Ferlay, Isabelle Soerjomataram et al.•International Journal of Cancer•2015

  • Natural Products As Sources of New Drugs over the 30 Years from 1981 to 2010

    David J Newman, Gordon M Cragg•Journal of natural products•2012

  • Plants as a source of anti-cancer agents

    Open Access•Gordon M Cragg, David J Newman•Journal of Ethnopharmacology•2005

  • Monoterpene bisindole alkaloids, from the African medicinal plant Tabernaemontana elegans, induce apoptosis in HCT116 human colon carcinoma cells

    Open Access•Tayyab A Mansoor, Pedro M Borralho et al.•Journal of Ethnopharmacology•2013

Citation velocityhistorical
Highly citedNo

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