Semen Strychni Pulveratum and vomicine alleviate neuroinflammation in amyotrophic lateral sclerosis through cGAS-STING-TBK1 pathway
Bibliographic Data
| ID | 14727599 |
|---|---|
| Authors | Yingshi Zhan (Guangzhou University of Chinese Medicine), Jingyan Huang (0009-0005-3899-9731, Guangzhou University of Chinese Medicine), Xiaohui Tang (0009-0005-7503-5683, Guangzhou University of Chinese Medicine), Baoxin Du (Guangzhou University of Chinese Medicine, corresponding author), Biying Yang (0000-0001-8890-954X, Guangzhou University of Chinese Medicine, corresponding author) |
| Year | 2025 |
| Volume | 336 |
| Pages | 118741 |
| Publication date | 2025-01-01 |
| Open Access | Yes |
| Type | ARTICLE |
| Venue | Journal of Ethnopharmacology (JOURNAL) |
| Journal identifiers | ISSN: 0378-8741 • E-ISSN: 1872-7573 |
| Publisher | Elsevier BV (PUBLISHER) |
| DOI | 10.1016/j.jep.2024.118741 |
| PMID | 39197801 |
| OpenAlex | W4401928442 |
| Language | EN |
| References cited | 38 |
This study demonstrated that SSP and vomicine exert neuroprotective and anti-neuroinflammatory effects in the treatment of ALS. SSP and vomicine may reduce neuroinflammation by regulating the cGAS-STING-TBK1 pathway, and could thereby play a role in ALS treatment
Amyotrophic lateral sclerosis · Biology · Disease · Neuroinflammation · Semen · interferon and immune responses · Medicine · Neuroinflammation and Neurodegeneration Mechanisms · Neuroscience · Peroxisome Proliferator-Activated Receptors · Anatomy · Internal Medicine
| Highly cited | No |
|---|