Flavonoid-rich Phyla nodiflora fraction promotes Keap1 degradation and Nrf2/HO-1 activation to attenuate particulate matter–induced oxidative stress in human keratinocytes
Bibliographic Data
| ID | 14727710 |
|---|---|
| Authors | Chia-Hsuan Lin (0000-0002-0898-2219, Kaohsiung Medical University), Jin-Ye Wu (Kaohsiung Medical University), Andrea Gu (Kaohsiung Medical University), Ho-Cheng Wu (Kaohsiung Medical University), Ho‐Cheng Wu (0000-0002-6648-6010, Kaohsiung Medical University), Yih-Fung Chen (Kaohsiung Medical University, corresponding author), Yih‐Fung Chen (0000-0002-5595-1319, Kaohsiung Medical University, corresponding author), Horng-Huey Ko (0000-0003-4203-0200, Kaohsiung Medical University, corresponding author) |
| Year | 2026 |
| Volume | 360 |
| Pages | 121168 |
| Publication date | 2026-04-01 |
| Peer Reviewed | Yes |
| Open Access | Yes |
| Type | ARTICLE |
| Venue | Journal of Ethnopharmacology (JOURNAL) |
| Journal identifiers | ISSN: 0378-8741 • E-ISSN: 1872-7573 |
| Publisher | Elsevier BV (PUBLISHER) |
| DOI | 10.1016/j.jep.2026.121168 |
| PMID | 41494610 |
| OpenAlex | W7118123810 |
| Language | EN |
| References cited | 56 |
Antioxidant · Biological activity · Fraction (chemistry · KEAP1 · Oxidative damage · Oxidative phosphorylation · Oxidative stress · Genomics, phytochemicals, and oxidative stress · Phytochemicals and Antioxidant Activities · Skin Protection and Aging
Particulate matter exposure in construction sites is associated with health effects in workers
Resveratrol targeting NRF2 disrupts the binding between Keap1 and NRF2-DLG motif to ameliorate oxidative stress damage in mice pulmonary infection
Eupafolin ameliorates COX-2 expression and PGE2 production in particulate pollutants-exposed human keratinocytes through ROS/Mapks pathways
Ethnopharmacological application of medicinal plants to cure skin diseases and in folk cosmetics among the tribal communities of North-West Frontier Province, Pakistan
Eupafolin, a skin whitening flavonoid isolated from Phyla nodiflora, downregulated melanogenesis
| Citation velocity | historical |
|---|---|
| Highly cited | No |