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Coumarins and flavones from Ficus erecta and their anti-inflammatory activity

Bibliographic Data

ID14728257
AuthorsAn Jin, Jin An (0000-0001-5416-2660, Hunan University), Yuyan Wang (0000-0003-3747-0762, Hunan University), Lingfei Tong (First Affiliated Hospital of Jiangxi Medical College), Guifeng Liu (0000-0001-7209-1632, Jiang Xi Institute for Drug Control), Jinglin Feng (Hunan University), Ying Li (0000-0003-0678-9535, Hunan University), Chengying Shen (0000-0002-6749-9120, Jiangxi Provincial People's Hospital), Wenming Wu (0009-0008-8770-6861, Jiangxi Provincial People's Hospital, corresponding author)
Year2024
Volume333
Pages118472
Publication date2024-10-01
Open AccessYes
TypeARTICLE
VenueJournal of Ethnopharmacology (JOURNAL)
Journal identifiersISSN: 0378-8741 • E-ISSN: 1872-7573
PublisherElsevier BV (PUBLISHER)
DOI10.1016/j.jep.2024.118472
PMID38901681
OpenAlexW4399814367
LanguageEN
Citations received2
References cited37

The current phytochemical investigations revealed that coumarins and flavones represent the primary chemical constituents of F. erecta. Compounds 7 and 17 exhibit potent anti-inflammatory properties, linked with the inhibition of NF-κB activation by preventing the degradation of IκBα phosphorylation. These compounds may serve as promising candidates for treating or preventing certain inflammatory diseases

Antioxidant · Biological activity · Biology · Botany · Ficus · Flavones · Flavonoid · In vitro · Moraceae · Pharmacognosy · Traditional medicine · Medicine · Phytochemistry and Bioactive Compounds · Phytochemistry and Biological Activities · Phytochemistry and biological activities of Ficus species · Biochemistry

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Citations per year2
Citation span2025 - 2026 (2)
Highly citedNo

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