Extracts of Benincasa hispida prevent development of experimental ulcers
Datos Bibliográficos
| ID | 14728290 |
|---|---|
| Autores | J K Grover (All India Institute of Medical Sciences, autor de correspondencia), G Adiga, Gowrav Perdur Adiga (All India Institute of Medical Sciences), V Vats (0009-0008-4598-7861, All India Institute of Medical Sciences), Satyajeet S Rathi (All India Institute of Medical Sciences) |
| Año | 2001 |
| Volumen | 78 |
| Número | 2-3 |
| Páginas | 159-164 |
| Fecha de publicación | 2001-12-01 |
| Peer Reviewed | Sí |
| Open Access | Sí |
| Tipo | ARTICLE |
| Revista | Journal of Ethnopharmacology (JOURNAL) |
| Identificadores de la revista | ISSN: 0378-8741 • E-ISSN: 1872-7573 |
| Editorial | Elsevier BV (PUBLISHER) |
| DOI | 10.1016/s0378-8741(01)00334-8 |
| PMID | 11694361 |
| OpenAlex | W2002733811 |
| Idioma | EN |
| Citas recibidas | 4 |
| Referencias citadas | 14 |
Benincasa hispida (B. hispida) is recommended in Ayurveda for the management of peptic ulcers. Therefore, anti-ulcerogenic activity of different extracts of B. hispida (fresh juice, supernatant and residue fraction of centrifuged juice, alcoholic and petroleum ether extract) were studied in aspirin plus restraint, swimming stress, indomethacin plus histamine and serotonin-induced ulcers in rats and mice. The oral feeding of different doses of the extract significantly reduced the ulcer index produced by various ulcerogens. The anti-ulcerogenic effect was dose-dependent in stress induced model of ulcer and not in other models. B. hispida probably has a CNS component in prevention of stress induced ulceration. However, antihistaminic, anti-cholinergic effects and prevention of disturbance in gastric micro-circulation as possible modes of action cannot be ruled out. Chronic toxicity studies carried out for 3 months revealed no deleterious effect of fresh juice of B. hispida on various hematological and biochemical parameters studied. Thus, extracts of B. hispida may be considered to be a drug of natural origin possessing anti-ulcer activity
Aspirin · Gastric mucosa · Histamine · Ranitidine · Stomach · Traditional medicine · Ulcer index · Advances in Cucurbitaceae Research · Chemistry · Medicine · Natural Products and Biological Research · Biochemistry · Pharmacology
Medicinal plants and formulations used by the Soren clan of the Santal Tribe in Rajshahi district, Bangladesh for treatment of various ailments
Hydroalcoholic extract of Benincasa hispida (Thunb.) Cogn. reinstates renal structural and functional dynamics compromised in diabetic mice
The methanolic extract of Boesenbergia rotunda (L.) Mansf. and its major compound pinostrobin induces anti-ulcerogenic property in vivo
Anti-angiogenic effect of the seed extract of Benincasa hispida Cogniaux
| Obras citantes distintas | 4 |
|---|---|
| Citas por año | 0,19 |
| Intervalo de citas | 2005 - 2026 (22) |
| Velocidad de citación | current |
| Altamente citado | No |
| Tipos de cita | Neutras: 3 |