Antinociceptive efficacy, chemistry, potential toxicity, and quality control procedures of Clinopodium macrostemum and Clinopodium mexicanum
A comparative analysis
Bibliographic Data
| ID | 14728815 |
|---|---|
| Authors | Gabriela García-Marín (Universidad Nacional Autonoma de Mexico), Gabriela García‐Marín (Universidad Nacional Autonoma de Mexico), Valeria Reyes-Pérez, Valeria Reyes‐Pérez (0000-0002-5535-7627, Universidad Autónoma de la Ciudad de México), Sol Cristian (0000-0002-0104-4852, Universidad Nacional Autonoma de Mexico), Sol Cristians, Isabel Rivero-Cruz, Isabel Rivero‐Cruz (0000-0003-0185-5775, Universidad Nacional Autonoma de Mexico), Omar Emiliano Aparicio-Trejo, Omar Emiliano Aparicio‐Trejo (0000-0002-7701-4537, Instituto Nacional de Cardiología), Rachel Mata (0000-0002-2861-2768, Universidad Nacional Autonoma de Mexico, corresponding author) |
| Year | 2026 |
| Volume | 357 |
| Pages | 120951 |
| Publication date | 2026-02-01 |
| Open Access | Yes |
| Type | ARTICLE |
| Venue | Journal of Ethnopharmacology (JOURNAL) |
| Journal identifiers | ISSN: 0378-8741 • E-ISSN: 1872-7573 |
| Publisher | Elsevier BV (PUBLISHER) |
| DOI | 10.1016/j.jep.2025.120951 |
| PMID | 41297727 |
| OpenAlex | W4416660103 |
| Language | EN |
| References cited | 33 |
The observed antinociceptive activity in both Clinopodium species is consistent with their reported pharmacological potential and traditional use. However, the acute renal injury associated with both plants requires further investigation. In contrast, variability in the volatilome between species may serve as a valuable tool for quality control. These differences in chemical composition suggest key avenues for distinguishing and effectively utilizing the species
Analgesic · Folk medicine · Nociception · Pharmacognosy · Drug-Induced Hepatotoxicity and Protection · Herbal Medicine Research Studies · Plant chemical constituents analysis
| Highly cited | No |
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