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Panax notoginseng saponins inhibit ischemia-induced apoptosis by activating PI3K/Akt pathway in cardiomyocytes

Datos Bibliográficos

ID14728873
AutoresShaoxian Chen (Guangdong Academy of Medical Sciences), Juli Liu (Shantou University Medical College), Xiaoying Liu (0000-0001-9897-1291, Guangdong Academy of Medical Sciences), Yongheng Fu, Yong‐Heng Fu (Guangdong General Hospital), Mengzhen Zhang (0009-0008-3368-074X, Guangdong Academy of Medical Sciences), Qiuxiong Lin, Qiu‐Xiong Lin (Guangdong Academy of Medical Sciences), Jiening Zhu, Jie-Ning Zhu (Guangdong Academy of Medical Sciences), Liping Mai (0000-0001-8644-2376, Guangdong General Hospital), Zhixin Shan, Zhi‐Xin Shan (0000-0001-6086-5565, Guangdong General Hospital), Xiyong Yu, Xi‐Yong Yu (Guangdong Academy of Medical Sciences), Min Yang (0000-0001-9017-5960, Guangdong Academy of Medical Sciences, autor de correspondencia), Shuguang Lin, Lin Shu-guang (Guangdong General Hospital)
Año2011
Volumen137
Número1
Páginas263-270
Fecha de publicación2011-09-01
Peer ReviewedSí
Open AccessSí
TipoARTICLE
RevistaJournal of Ethnopharmacology (JOURNAL)
Identificadores de la revistaISSN: 0378-8741 • E-ISSN: 1872-7573
EditorialElsevier BV (PUBLISHER)
DOI10.1016/j.jep.2011.05.011
PMID21619920
OpenAlexW2030158479
IdiomaEN
Citas recibidas8
Referencias citadas29

Apoptosis · Araliaceae · Biological activity · Folk medicine · Ginseng · In vitro · Ischemia · Panax notoginseng · Pathology · Pharmacognosy · PI3K/AKT/mTOR pathway · Protein kinase B · Signal transduction · Traditional medicine · Cell death mechanisms and regulation · Chemistry · Ginseng Biological Effects and Applications · Medicine · Pharmacological Effects of Natural Compounds · Biochemistry · Internal Medicine · Pharmacology

  • Global gene expression analysis using RNA-seq reveals the new roles of Panax notoginseng Saponins in ischemic cardiomyocytes

    Open Access•Shaoxian Chen, Yueheng Wu et al.•Journal of Ethnopharmacology•2021

  • Amelioration of acute myocardial infarction by saponins from flower buds of Panax notoginseng via pro-angiogenesis and anti-apoptosis

    Open Access•Bin-Rui Yang, Kwok-Kuen Cheung et al.•Journal of Ethnopharmacology•2016

  • Systems pharmacology reveals the multi-level synergetic mechanism of action of Ginkgo biloba L. leaves for cardiomyopathy treatment

    Open Access•Yueping Li, Chi Xu et al.•Journal of Ethnopharmacology•2021

  • Systematically characterized mechanism of treatment for lumbar disc herniation based on Yaobitong capsule ingredient analysis in rat plasma and its network pharmacology strategy by UPLC-MS/MS

    Open Access•Yajie Deng, Xun Gao et al.•Journal of Ethnopharmacology•2020

  • Total saponins of panaxnotoginseng promotes lymphangiogenesis by activation Vegf-C expression of lymphatic endothelial cells

    Open Access•Jinlong Li, Yan Chen et al.•Journal of Ethnopharmacology•2016

  • Shenyuan, an extract of American Ginseng and Corydalis Tuber formula, attenuates cardiomyocyte apoptosis via inhibition of endoplasmic reticulum stress and oxidative stress in a porcine model of acute myocardial infarction

    Open Access•Xin-Yuan Zhu, Xinyuan Zhu et al.•Journal of Ethnopharmacology•2013

  • Panax ginseng against myocardial ischemia/reperfusion injury

    Open Access•Jinjin Chen, Qingxia Huang et al.•Journal of Ethnopharmacology•2023

  • Panax notoginseng saponins provide neuroprotection by regulating NgR1/RhoA/Rock2 pathway expression, in vitro and in vivo

    Open Access•Xiaowei Shi, Wenjing Yu et al.•Journal of Ethnopharmacology•2016

  • Total saponins of Panax Notoginseng modulate the expression of caspases and attenuate apoptosis in rats following focal cerebral ischemia-reperfusion

    Open Access•Hua Li, Chang-Qing Deng et al.•Journal of Ethnopharmacology•2009

Obras citantes distintas8
Citas por año0,62
Intervalo de citas2013 - 2023 (11)
Velocidad de citaciónhistorical
Altamente citadoNo
Tipos de citaNeutras: 8
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