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Crocetin ameliorates chronic restraint stress-induced depression-like behaviors in mice by regulating MEK/ERK pathways and gut microbiota

Bibliographic Data

ID14729244
AuthorsSusu Lin (Zhejiang University of Technology), Qiaoqiao Li (0000-0001-9710-7135, Zhejiang University of Technology), Shanshan Jiang (0000-0002-0284-8780, Zhejiang University of Technology), Zijin Xu (0000-0003-2747-8373, Zhejiang University of Technology), Yu Jiang (0000-0001-8828-7832, Zhejiang University of Technology), Ling Liu (0000-0001-5231-9396, Zhejiang University of Technology), Jinyan Jiang (0000-0001-6963-7200, Zhejiang University of Technology), Yingpeng Tong (0000-0002-6643-1132, Taizhou University, corresponding author), Ping Wang (0000-0001-6354-2235, Zhejiang University of Technology, corresponding author)
Year2021
Volume268
Pages113608
Publication date2021-03-01
Peer ReviewedYes
Open AccessYes
TypeARTICLE
VenueJournal of Ethnopharmacology (JOURNAL)
Journal identifiersISSN: 0378-8741 • E-ISSN: 1872-7573
PublisherElsevier BV (PUBLISHER)
DOI10.1016/j.jep.2020.113608
PMID33242618
OpenAlexW3109023111
LanguageEN
Citations received4
References cited80

Alkaline phosphatase · Antidepressant · Aspartate transaminase · Behavioural despair test · Brain-derived neurotrophic factor · Carotenoid · Chronic stress · CREB · Crocetin · Ginseng · Hippocampus · Kinase · MAPK/ERK pathway · Neurotrophic factors · Pathology · Receptor · Tail suspension test · Transcription factor · Biochemical effects in animals · Chemistry · Medicinal Plants and Bioactive Compounds · Medicine · Saffron Plant Research Studies · Biochemistry · Endocrinology · Internal Medicine · Pharmacology

  • Saffron (Crocus sativus L.)

    Open Access•Mengzhen Wei, Qiong Zhang et al.•Journal of Ethnopharmacology•2026

  • Crocetin ameliorates non-alcoholic fatty liver disease by modulating mitochondrial dysfunction in L02 cells and zebrafish model

    Open Access•Zijin Xu, Susu Lin et al.•Journal of Ethnopharmacology•2022

  • Traditional Chinese herbal formula, Fuzi-Lizhong pill, produces antidepressant-like effects in chronic restraint stress mice through systemic pharmacology

    Open Access•Fangyi Zhao, Jingjing Piao et al.•Journal of Ethnopharmacology•2025

  • Saffron essential oil ameliorates Cums-induced depression-like behavior in mice via the Mapk-CREB1-BDNF signaling pathway

    Open Access•Ziwei Chen, Jinping Gu et al.•Journal of Ethnopharmacology•2023

  • Evaluation of Outcomes With Citalopram for Depression Using Measurement-Based Care in STAR*D

    Madhukar H Trivedi, A John Rush et al.•American Journal of Psychiatry•2006

  • Global, regional, and national incidence, prevalence, and years lived with disability for 328 diseases and injuries for 195 countries, 1990–2016

    Open Access•Theo Vos, Amanuel Alemu Abajobir et al.•The Lancet•2017

  • Major depressive disorder

    Open Access•Christian Otte, Stefan M Gold et al.•Nature Reviews Disease Primers•2016

  • Global, regional, and national incidence, prevalence, and years lived with disability for 354 diseases and injuries for 195 countries and territories, 1990–2017

    Open Access•L James, Spencer L James et al.•The Lancet•2018

  • Akebia quinata Decaisne aqueous extract acts as a novel anti-fatigue agent in mice exposed to chronic restraint stress

    Open Access•Sun Haeng Park, Seol Jang et al.•Journal of Ethnopharmacology•2018

Unique citing works4
Citations per year1
Citation span2022 - 2026 (5)
Citation velocitycurrent
Highly citedNo
Citation typesNeutral: 4

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