Jianpi Jiedu decoction, a traditional Chinese medicine formula, inhibits tumorigenesis, metastasis, and angiogenesis through the mTOR/HIF-1α/Vegf pathway
Bibliographic Data
| ID | 14729358 |
|---|---|
| Authors | WeiJun Peng (0000-0002-4506-0942, Central South University), Shaofang Zhang (Central South University, corresponding author), Zheyu Zhang (0000-0003-0768-2713, Central South University), Panpan Xu (0000-0002-5932-1429, Central South University), Dan Mao (0000-0003-1944-7016, Central South University), Siqi Huang (0009-0006-5961-1799, Central South University), Biyue Chen (Central South University), Chunhu Zhang (0000-0001-8829-3319, Central South University), Sifang Zhang (0000-0002-6540-1855, Central South University) |
| Year | 2018 |
| Volume | 224 |
| Pages | 140-148 |
| Publication date | 2018-10-01 |
| Peer Reviewed | Yes |
| Open Access | Yes |
| Type | ARTICLE |
| Venue | Journal of Ethnopharmacology (JOURNAL) |
| Journal identifiers | ISSN: 0378-8741 • E-ISSN: 1872-7573 |
| Publisher | Elsevier BV (PUBLISHER) |
| DOI | 10.1016/j.jep.2018.05.039 |
| PMID | 29852266 |
| OpenAlex | W2807360026 |
| Language | EN |
| Citations received | 1 |
| References cited | 44 |
JPJD treatment produced anti-colorectal tumor effects by inhibiting tumorigenesis, metastasis, as well as angiogenesis through the mTOR/HIF-1α/VEGF pathway. Thus, these results provide a strong rationale for the therapeutic use of JPJD in cancer treatment. Further studies are required to investigate the mechanisms underlying anti-CRC effect of JPJD
Angiogenesis · Apoptosis · Biology · Cancer · Carcinogenesis · Cell growth · Colorectal cancer · In vivo · Metastasis · MTT assay · PI3K/AKT/mTOR pathway · Protein kinase B · Cancer Mechanisms and Therapy · Cancer, Hypoxia, and Metabolism · Colorectal Cancer Treatments and Studies · Medicine · Biochemistry · Cancer Research · Internal Medicine
Rhizoma Amorphophalli inhibits TNBC cell proliferation, migration, invasion and metastasis through the PI3K/Akt/mTOR pathway
Induction of cell cycle arrest and apoptosis by betulinic acid-rich fraction from Dillenia suffruticosa root in MCF-7 cells involved p53/p21 and mitochondrial signalling pathway
| Unique citing works | 1 |
|---|---|
| Citations per year | 0,25 |
| Citation span | 2022 - 2022 (1) |
| Citation velocity | historical |
| Highly cited | No |
| Citation types | Neutral: 1 |