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Gubi Zhitong formula alleviates knee osteoarthritis induced by excessive mechanical loading in rats via regulating Piezo1 mediated Ca2+ signaling pathway and phosphoinositide 3-Kinase / protein kinase B / nuclear factor kappa-B axis

Bibliographic Data

ID14729945
AuthorsZhenwei Zhou (0000-0003-4473-7541, Changchun University of Chinese Medicine), Yunfei Li (0000-0002-0542-4641, Changchun University of Chinese Medicine), Kai Xi (Changchun University of Chinese Medicine), Yongji Wu (Changchun University of Chinese Medicine), Yuyan Jia (0000-0002-5303-3821, Changchun University of Chinese Medicine), Y Si (0000-0003-0780-635X, Changchun University of Chinese Medicine), Xukai Wang (0000-0003-4941-3714, Changchun University of Chinese Medicine, corresponding author), Haisi Dong (0000-0003-2172-2312, Changchun University of Chinese Medicine, corresponding author), Xiangyang Leng (0000-0001-5278-4001, Changchun University of Chinese Medicine, corresponding author)
Year2026
Volume356
Pages120831
Publication date2026-02-01
Peer ReviewedYes
Open AccessYes
TypeARTICLE
VenueJournal of Ethnopharmacology (JOURNAL)
Journal identifiersISSN: 0378-8741 • E-ISSN: 1872-7573
PublisherElsevier BV (PUBLISHER)
DOI10.1016/j.jep.2025.120831
PMID41173085
OpenAlexW4415679819
LanguageEN
Citations received1
References cited33

Kinase · NF-κB · Osteoarthritis · Phosphoinositide 3-kinase · PI3K/AKT/mTOR pathway · Protein kinase A · Signal transduction · Transcriptome · Erythrocyte Function and Pathophysiology · Osteoarthritis Treatment and Mechanisms · Pain Mechanisms and Treatments

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Unique citing works1
Citations per year1
Citation span2026 - 2026 (1)
Citation velocitycurrent
Highly citedNo
Citation typesNeutral: 1
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