Mechanism of Shashen-Maidong herb pair in treating hepatocellular carcinoma using network pharmacology and experimental validation

Bibliographic Data

ID14731609
AuthorsYuqing Xie (0000-0001-5720-6649, Beijing Ditan Hospital), Yu-Qing Xie, Feng-Na Yan, Fengna Yan (Beijing Ditan Hospital), Li-Hua Yu, Lihua Yu (0009-0005-2751-5594, Beijing Ditan Hospital), Hui-Wen Yan, Huiwen Yan (0000-0001-6265-7719, Beijing Ditan Hospital), Ya-Xian Kong, Yaxian Kong (0000-0003-2804-8682, Beijing Ditan Hospital, corresponding author), Zhi-Yun Yang (0000-0002-1522-0749, Beijing Ditan Hospital, corresponding author)
Year2025
Volume337
IssuePt 3
Pages118954
Publication date2025-01-01
Open AccessYes
TypeARTICLE
VenueJournal of Ethnopharmacology (JOURNAL)
Journal identifiersISSN: 0378-8741 • E-ISSN: 1872-7573
PublisherElsevier BV (PUBLISHER)
DOI10.1016/j.jep.2024.118954
PMID39419302
OpenAlexW4403456979
LanguageEN
References cited45

This study identified the key components, targets, and signaling pathways of the SS-MD herb pair, confirm that SS-MD herb pair play an immunomodulatory role in treating HCC, provides theoretical support for the collaborative treatment of HCC with TCM

Biological activity · Biology · Hepatocellular carcinoma · Herb · In vitro · Mechanism (biology · Medicinal herbs · Pharmacognosy · Traditional medicine · Computational Drug Discovery Methods · Medicine · Pharmacological Effects of Natural Compounds · Philosophy · Traditional Chinese Medicine Analysis · Genetics · Internal Medicine · Pharmacology

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Open DOIOpen Access