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Triptolide

Progress on research in pharmacodynamics and toxicology

Bibliographic Data

ID14731981
AuthorsXiao-Jiaoyang Li, Xiaojiaoyang Li (0000-0003-0291-5856, China Pharmaceutical University), Zhenzhou Jiang (0000-0002-0420-0822, China Pharmaceutical University, corresponding author), Zhen-Zhou Jiang, Luyong Zhang (0000-0003-1164-7371, China Pharmaceutical University), Lu-yong Zhang
Year2014
Volume155
Issue1
Pages67-79
Publication date2014-08-01
Peer ReviewedYes
Open AccessYes
TypeARTICLE
VenueJournal of Ethnopharmacology (JOURNAL)
Journal identifiersISSN: 0378-8741 • E-ISSN: 1872-7573
PublisherElsevier BV (PUBLISHER)
DOI10.1016/j.jep.2014.06.006
PMID24933225
OpenAlexW2031378528
LanguageEN
Citations received16
References cited119

Alternative medicine · Biology · Pathology · Traditional Chinese medicine · Traditional medicine · Tripterygium · Tripterygium wilfordii · Triptolide · Flavonoids in Medical Research · Medicine · Natural Compounds in Disease Treatment · Natural product bioactivities and synthesis · Pharmacology

  • Effect of Triptolide on Proliferation and Apoptosis of Angiotensin Ii-Induced Cardiac Fibroblasts in Vitro

    Open Access•Mao Liu, James Yeh et al.•African Journal of Traditional…•2016

  • Wu Zi Yan Zong Wan Improves Triptolide-Induced Testicular Spermatogenic Dysfunction Through the Spermatogenic Microenvironment and the PLCγ/PKC Pathway

    Open Access•Lei Zhang, Binghao Bao et al.•American Journal of Men s Health•2025

  • Processing with Cuscuta chinensis Lam. juice mitigates Tripterygium wilfordii Hook.F. toxicity via a multi-mechanistic approach and enhances its anti-rheumatic efficacy

    Open Access•Tianzhu Zhang, Junming Wang et al.•Journal of Ethnopharmacology•2026

  • Th17/Treg imbalance mediates hepatic intolerance to exogenous lipopolysaccharide and exacerbates liver injury in triptolide induced excessive immune response

    Open Access•Haoran Zhang, Ziqiao Yuan et al.•Journal of Ethnopharmacology•2022

  • Potential shared therapeutic and hepatotoxic mechanisms of Tripterygium wilfordii polyglycosides treating three kinds of autoimmune skin diseases by regulating IL-17 signaling pathway and Th17 cell differentiation

    Open Access•Yi Chen, Yongfang Wang et al.•Journal of Ethnopharmacology•2022

  • Integrated strategy of LC-MS and network pharmacology for predicting active constituents and pharmacological mechanisms of Ranunculus japonicus Thunb. for treating rheumatoid arthritis

    Open Access•Zhaoyi Wang, Zhao-Yi Wang et al.•Journal of Ethnopharmacology•2021

  • Clinical efficacy and molecular mechanism of Chinese medicine in the treatment of autoimmune thyroiditis

    Open Access•Ling Zhou, Jinli Luo et al.•Journal of Ethnopharmacology•2024

  • CDCS-TCM

    Open Access•Jiaxuan Gao, Xiaoyang Xiang et al.•Journal of Ethnopharmacology•2024

  • Increased involvement of Panax notoginseng in the mechanism of decreased hepatotoxicity induced by Tripterygium wilfordii in rats

    Open Access•Benyong Zhang, Qichun Zhang et al.•Journal of Ethnopharmacology•2016

  • Role of MicroRNA-155 in Triptolide-induced hepatotoxicity via the Nrf2-Dependent pathway

    Open Access•Yao Li, Lin Guo et al.•Journal of Ethnopharmacology•2021

  • Investigation of the active components in Tripterygium wilfordii leading to its acute hepatotoxicty and nephrotoxicity

    Open Access•Xin-Xiu Li, Fu-Ying Du et al.•Journal of Ethnopharmacology•2015

  • Effects of heat-processed Gynostemma pentaphyllum on high-fat diet-fed mice of obesity and functional analysis on network pharmacology and molecular docking strategy

    Open Access•Peng Xie, Mei Guo et al.•Journal of Ethnopharmacology•2022

  • Triptolide -induced hepatotoxicity can be alleviated when combined with Panax notoginseng saponins and Catapol

    Open Access•Lingling Zhou, Cong Zhou et al.•Journal of Ethnopharmacology•2018

  • Cytotoxic terpenoids from Tripterygium hypoglaucum against human pancreatic cancer cells SW1990 by increasing the expression of Bax protein

    Open Access•Xing-Long Chen, Xing‐Long Chen et al.•Journal of Ethnopharmacology•2022

  • The protective effect and molecular mechanism of glycyrrhizic acid glycosides against Tripterygium glycosides induced nephrotoxicity based on the RhoA/Rock1 signalling pathway

    Open Access•Liu Zhou, Zhou Liu et al.•Journal of Ethnopharmacology•2024

  • Saikosaponin a activates tet1/dll3/notch1 signalling and promotes hippocampal neurogenesis to improve depression-like behavior in mice

    Open Access•Yue Tong, Ge Zhao et al.•Journal of Ethnopharmacology•2024

  • Toxicogenomic analysis of the gene expression changes in rat liver after a 28-day oral Tripterygium wilfordii multiglycoside exposure

    Open Access•Yun Zhang, Zhenzhou Jiang et al.•Journal of Ethnopharmacology•2012

  • Glycyrrhizin accelerates the metabolism of triptolide through induction of CYP3A in rats

    Open Access•Ting Tai, Xin Huang et al.•Journal of Ethnopharmacology•2014

Unique citing works16
Citations per year1,45
Citation span2015 - 2026 (12)
Citation velocitycurrent
Highly citedNo
Citation typesNeutral: 15

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