MiRNA and miRNA target genes in intervention effect of Zhuyu pill on cholestatic rat model

Bibliographic Data

ID14732346
AuthorsHan Yu (0000-0002-7103-1416, Chengdu University of Traditional Chinese Medicine), Chao Liu (0000-0001-9257-4519, Chengdu University of Traditional Chinese Medicine), Jianfei Wang (0000-0002-1535-5512, Chinese Academy of Medical Sciences & Peking Union Medical College), Jun Han (0000-0002-7286-062X, Chengdu University of Traditional Chinese Medicine), Fenghua Zhang (0000-0002-1666-9548, Chengdu University of Traditional Chinese Medicine), Xin Zhou (0000-0003-2640-6431, Chengdu University of Traditional Chinese Medicine), Yueqiang Wen (0000-0001-8867-7187, Chengdu University of Traditional Chinese Medicine, corresponding author), Tao Shen (0000-0002-2261-5300, Chengdu University of Traditional Chinese Medicine, corresponding author)
Year2022
Volume283
Pages114709
Publication date2022-01-01
Open AccessYes
TypeARTICLE
VenueJournal of Ethnopharmacology (JOURNAL)
Journal identifiersISSN: 0378-8741 • E-ISSN: 1872-7573
PublisherElsevier BV (PUBLISHER)
DOI10.1016/j.jep.2021.114709
PMID34626777
OpenAlexW3203210534
LanguageEN
References cited51

ZYP can significantly reduce liver biochemical indices and improve liver tissue damage in cholestasis rats through the regulation of miRNA expression in the liver, producing a positive regulatory effect on bile excretion-related genes

Biology · Cholestasis · Deep sequencing · Gene · Gene expression · Mechanism of Action · Microarray · microRNA · Cholangiocarcinoma and Gallbladder Cancer Studies · Drug Transport and Resistance Mechanisms · Hepatitis B Virus Studies · Medicine · Endocrinology · Genetics · Pharmacology

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