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Wuzi Yanzong administration alleviates Sertoli cell injury by recovering AKT/mTOR-mediated autophagy and the mTorc1–mTROC2 balance in aging-induced testicular dysfunction

Bibliographic Data

ID14733151
AuthorsYanyu Chang (0000-0002-3226-1008, China Three Gorges University), He Deng (China Three Gorges University), Yumin He (0000-0002-9717-5311, China Three Gorges University), Benwen Zhou (China Three Gorges University), Ding Yuan (0000-0001-8066-8155, China Three Gorges University), Jie Wu (0000-0002-1389-6964, China Three Gorges University), Changcheng Zhang (0000-0002-1839-9377, China Three Gorges University, corresponding author), Haixia Zhao (0000-0002-0120-246X, China Three Gorges University, corresponding author)
Year2024
Volume318
IssuePt A
Pages116865
Publication date2024-01-01
Peer ReviewedYes
Open AccessYes
TypeARTICLE
VenueJournal of Ethnopharmacology (JOURNAL)
Journal identifiersISSN: 0378-8741 • E-ISSN: 1872-7573
PublisherElsevier BV (PUBLISHER)
DOI10.1016/j.jep.2023.116865
PMID37422101
OpenAlexW4383315449
LanguageEN
Citations received2
References cited33

Apoptosis · Autophagy · Biology · mTORC1 · PI3K/AKT/mTOR pathway · Protein kinase B · Sertoli cell · Spermatogenesis · Autophagy in Disease and Therapy · Medicine · Natural Compounds in Disease Treatment · Sperm and Testicular Function · Biochemistry · Endocrinology · Internal Medicine · Pharmacology

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  • In vivo and in vitro protective effects of the Wuzi Yanzong pill against experimental spermatogenesis disorder by promoting germ cell proliferation and suppressing apoptosis

    Open Access•Wang-qian Chen, Wangqian Chen et al.•Journal of Ethnopharmacology•2021

  • Wu-Zi-Yan-Zong-Wan protects mouse blood-testis barrier from Tripterygium wilfordii Hook. f. multiglycoside-induced disruption by regulating proinflammatory cytokines

    Open Access•Zhenkun Pan, Zhen-Kun Pan et al.•Journal of Ethnopharmacology•2021

  • Wuzi-Yanzong-Wan prevents oligoasthenospermia due to TAp73 suppression by affecting cellular junction remodeling in testicular tissue in mice

    Open Access•Deling Wu, Tongsheng Wang et al.•Journal of Ethnopharmacology•2023

Unique citing works2
Citations per year1
Citation span2024 - 2025 (2)
Citation velocityrecent
Highly citedNo
Citation typesNeutral: 2

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