Saponin of Aralia taibaiensis promotes angiogenesis through Vegf/VEGFR2 signaling pathway in cerebral ischemic mice
Bibliographic Data
| ID | 14733248 |
|---|---|
| Authors | Xingru Tao (Xijing Hospital), Kedi Liu (0000-0002-0355-1807), Weihong Li (0000-0002-7775-1342, Shaanxi University of Chinese Medicine), Shi Zhao (0000-0001-8722-6149), Chengzhao Liu (Shaanxi University of Chinese Medicine), Qi Dai (0000-0003-2675-6511, Shaanxi University of Chinese Medicine), Taiwei Dong (Shaanxi University of Chinese Medicine), Peifeng Wei (0000-0003-2142-4155, corresponding author), Jialin Duan (0000-0002-6887-3866, Northwestern Polytechnical University, corresponding author), Jingwen Wang (0009-0000-7615-2674, Xijing Hospital, corresponding author), Miaomiao Xi (0000-0002-4367-2056, corresponding author) |
| Year | 2023 |
| Volume | 317 |
| Pages | 116771 |
| Publication date | 2023-12-01 |
| Open Access | Yes |
| Type | ARTICLE |
| Venue | Journal of Ethnopharmacology (JOURNAL) |
| Journal identifiers | ISSN: 0378-8741 • E-ISSN: 1872-7573 |
| Publisher | Elsevier BV (PUBLISHER) |
| DOI | 10.1016/j.jep.2023.116771 |
| PMID | 37308026 |
| OpenAlex | W4380150385 |
| Language | EN |
| Citations received | 2 |
| References cited | 55 |
The results proved that sAT promotes angiogenesis in cerebral ischemia-reperfusion mice and its mechanism is to regulate VEGF/VEGFR2 and then regulate Src/eNOS and PLCγ1/ERK1/2
Angiogenesis · Biology · Brain ischemia · CD31 · In vitro · In vivo · Ischemia · Microvessel · Neovascularization · Umbilical vein · Vascular endothelial growth factor · Angiogenesis and VEGF in Cancer · Medicine · Neuroinflammation and Neurodegeneration Mechanisms · Neurological Disease Mechanisms and Treatments · Biochemistry · Cancer Research · Internal Medicine · Pharmacology
| Citations per year | 2 |
|---|---|
| Citation span | 2025 - 2026 (2) |
| Highly cited | No |