Mechanism by which Eucommia ulmoides leaves Regulate Nonalcoholic fatty liver disease based on system pharmacology

Bibliographic Data

ID14733675
AuthorsMan Gong (First Affiliated Hospital of Henan University), Chengfu Su, Cheng-Fu Su (0000-0001-6479-3271, Hong Kong Baptist University), Mengzhe Fan (0000-0002-0624-8467, First Affiliated Hospital of Henan University), Ping Wang (0000-0001-6354-2235, First Affiliated Hospital of Henan University), Bingdi Cui (First Affiliated Hospital of Henan University), Zhongyuan Guo (0000-0003-2406-3877, Chinese Academy of Medical Sciences & Peking Union Medical College), Shaojia Liang, Lianhe Yang, Lian-He Yang (0000-0001-6002-474X, First Affiliated Hospital of Henan University), Xiaoqian Liu (0000-0003-4886-7837, Chinese Academy of Medical Sciences & Peking Union Medical College), Liping Dai, Li-ping Dai (0000-0002-1910-7591, Henan University of Traditional Chinese Medicine, corresponding author), Zhimin Wang (0000-0001-5089-977X, Chinese Academy of Medical Sciences & Peking Union Medical College, corresponding author)
Year2022
Volume282
Pages114603
Publication date2022-01-01
Open AccessYes
TypeARTICLE
VenueJournal of Ethnopharmacology (JOURNAL)
Journal identifiersISSN: 0378-8741 • E-ISSN: 1872-7573
PublisherElsevier BV (PUBLISHER)
DOI10.1016/j.jep.2021.114603
PMID34496264
OpenAlexW3196313580
LanguageEN
Citations received1
References cited35

The active ingredients in E. ulmoides leaves regulating nonalcoholic fatty liver disease are mainly flavonoids and phenolics. EUL 50 may play a role in lowering lipids by regulating PPARγ expression through inducing autophagy

Autophagy · Biology · Disease · Eucommia ulmoides · Fatty liver · Lipid metabolism · Nonalcoholic fatty liver disease · Pathology · Pogostemon · Traditional Chinese medicine · Traditional medicine · Chemistry · Genomics, phytochemicals, and oxidative stress · Lipid metabolism and biosynthesis · Liver Disease Diagnosis and Treatment · Medicine · Biochemistry · Internal Medicine · Pharmacology

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