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Rapid antidepressant effects of Aurantii Fructus are mediated by hypoxanthine-caspase-4 axis in Cums mice

Bibliographic Data

ID14733829
AuthorsChao Lü (0000-0003-4747-4943, Nanjing University of Chinese Medicine), Liyuan Tian (Nanjing University of Chinese Medicine), Zixuan Wei (0000-0002-3589-1179, Nanjing University of Chinese Medicine), Yiran Jiang (0000-0003-2078-8125, Nanjing University of Chinese Medicine), Mengqi Shao (0000-0001-5996-7783, Nanjing University of Chinese Medicine), Yaping Zhu (Nanjing University of Chinese Medicine), Lei Wu (0000-0002-0818-7338, Nanjing University of Chinese Medicine, corresponding author)
Year2026
Volume362
Pages121330
Publication date2026-05-01
Peer ReviewedYes
Open AccessYes
TypeARTICLE
VenueJournal of Ethnopharmacology (JOURNAL)
Journal identifiersISSN: 0378-8741 • E-ISSN: 1872-7573
PublisherElsevier BV (PUBLISHER)
DOI10.1016/j.jep.2026.121330
PMID41651039
OpenAlexW7127595282
LanguageEN
References cited39

Animal models of depression · Antidepressant · Depression (economics · Mechanism (biology · Mechanism of Action · Purinergic receptor · Medicinal Plant Extracts Effects · Treatment of Major Depression · Tryptophan and brain disorders

  • The role of inflammation in depression

    Open Access•Abraham H Miller, Andrew H Miller et al.•Nature Reviews Immunology•2016

  • Comparative efficacy and acceptability of 21 antidepressant drugs for the acute treatment of adults with major depressive disorder

    Open Access•Andrea Cipriani, Toshi A Furukawa et al.•The Lancet•2018

  • An integrated study of metabolomics and transcriptomics to reveal the anti-primary dysmenorrhea mechanism of Akebiae Fructus

    Open Access•Baolian Ma, Shilin Yang et al.•Journal of Ethnopharmacology•2021

  • Comparison of the chemical constituents of raw Fructus Aurantii and Fructus Aurantii stir-baked with bran, and the biological effects of auraptene

    Open Access•Yangang Li, Yan-Gang Li et al.•Journal of Ethnopharmacology•2021

  • Xiaoyaosan against depression through suppressing LPS mediated TLR4/NLRP3 signaling pathway in “microbiota-gut-brain” axis

    Open Access•Xiaojie Liu, Huimin Liu et al.•Journal of Ethnopharmacology•2024

Citation velocityhistorical
Highly citedNo

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