Protective effect of Huyang Yangkun Formula on ovarian function in premature ovarian insufficiency rats based on apoptotic mechanism

Bibliographic Data

ID14734854
AuthorsLingdi Wang (0000-0002-0150-1478, Guangzhou University of Chinese Medicine), Meifang Li (0000-0002-9138-3080, Shanxi Province Hospital of Traditional Chinese Medicine), Jian Liu (0000-0002-1447-0973, Guangzhou University of Chinese Medicine), Guangning Nie (Guangzhou University of Chinese Medicine), Li Yang (0000-0003-3852-3651, Guangzhou University of Chinese Medicine, corresponding author), Yang Li (0000-0002-2835-6661), Hongyan Yang (0009-0005-6810-9082, Guangzhou University of Chinese Medicine, corresponding author)
Year2021
Volume280
Pages114477
Publication date2021-11-01
Peer ReviewedYes
Open AccessYes
TypeARTICLE
VenueJournal of Ethnopharmacology (JOURNAL)
Journal identifiersISSN: 0378-8741 • E-ISSN: 1872-7573
PublisherElsevier BV (PUBLISHER)
DOI10.1016/j.jep.2021.114477
PMID34343645
OpenAlexW3188158128
LanguageEN
Citations received2
References cited34

This study evaluated the treatment effect of HYF on POI in rats. It showed that HYF could promote the follicles development by regulating AQP8/Bcl-2 family-related mitochondrial apoptosis, which provides basic evidence for TCM as an alternative therapy for POI

Andrology · Apoptosis · Biology · Corpus luteum · Downregulation and upregulation · Estradiol valerate · Hormone · Immunohistochemistry · Infertility · Ovarian reserve · Ovary · Pregnancy · Premature ovarian insufficiency · TUNEL assay · Medicine · Reproductive Biology and Fertility · Reproductive Physiology in Livestock · Reproductive System and Pregnancy · Endocrinology · Internal Medicine

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