Integrated pharmacokinetic properties, tissue distribution and metabolism of multiple active constituents in DBD for the treatment of GEM-induced myelosuppression
Bibliographic Data
| ID | 14734969 |
|---|---|
| Authors | Xiaodan Qi (0000-0001-6383-7877, Hebei Medical University), Lujie Zuo (0009-0001-3968-6906, Hebei Medical University), Chunxiao Chen (0000-0002-7863-7859, Hebei Medical University), Yuting Zhang (0000-0002-6460-6779, Hebei Medical University), Pengcheng Zhang (0000-0002-4546-0022, Hebei Medical University), Mei Han (0000-0002-3123-2205, Hebei Medical University), Dexuan Liu (Hebei Medical University), Meiping Ni (Obstetrics and Gynecology Hospital of Fudan University, corresponding author), Qingzhong Jia (0000-0001-9193-5087, Hebei Medical University, corresponding author), Yan Liu (0000-0002-1612-779X, Hebei Medical University, corresponding author) |
| Year | 2026 |
| Volume | 359 |
| Pages | 121084 |
| Publication date | 2026-03-01 |
| Open Access | Yes |
| Type | ARTICLE |
| Venue | Journal of Ethnopharmacology (JOURNAL) |
| Journal identifiers | ISSN: 0378-8741 • E-ISSN: 1872-7573 |
| Publisher | Elsevier BV (PUBLISHER) |
| DOI | 10.1016/j.jep.2025.121084 |
| PMID | 41443483 |
| OpenAlex | W7116889872 |
| Language | EN |
| References cited | 38 |
Distribution (mathematics · In vitro · In vivo · Metabolism · Pharmacokinetics · Tissue distribution · Glycosylation and Glycoproteins Research · Immune cells in cancer · Nanoparticle-Based Drug Delivery
Multi-tissue metabolomics and network pharmacology study on the intervention of Danggui Buxue Decoction in mice with gemcitabine induced myelosuppression
Pharmacokinetic comparison of seven major bio-active components in normal and blood deficiency rats after oral administration of Danggui Buxue decoction by UPLC-TQ/MS
Danggui Buxue Tang promotes the adhesion and migration of bone marrow stromal cells via the focal adhesion pathway in vitro
Danggui Buxue Decoction enhances the anticancer activity of gemcitabine and alleviates gemcitabine-induced myelosuppression
| Highly cited | No |
|---|