Study on the mechanism of Sangbaipi Decoction in treating acute lung injury via the inflammasome NLRP3 signaling pathway
Bibliographic Data
| ID | 14735115 |
|---|---|
| Authors | Baojun Xu (0000-0003-0739-3735, Changchun University of Chinese Medicine), Bijun Xu, Yuejie Wang (0000-0003-0422-8072, Changchun University of Chinese Medicine), Yang Xu (0000-0003-3898-022X, Baicheng Normal University), Xinjie Zhang (0000-0002-3194-7518, Changchun University of Chinese Medicine), Xiaoya Wang (0000-0003-0519-8661, Changchun University of Chinese Medicine), Siyu Chen (0000-0002-9712-9796, Changchun University of Chinese Medicine), Lijing Li (0000-0002-9469-1644, Changchun University of Chinese Medicine, corresponding author), Huiwei Bao (0000-0002-5787-1814, Changchun University of Chinese Medicine, corresponding author) |
| Year | 2026 |
| Volume | 357 |
| Pages | 120908 |
| Publication date | 2026-02-01 |
| Open Access | Yes |
| Type | ARTICLE |
| Venue | Journal of Ethnopharmacology (JOURNAL) |
| Journal identifiers | ISSN: 0378-8741 • E-ISSN: 1872-7573 |
| Publisher | Elsevier BV (PUBLISHER) |
| DOI | 10.1016/j.jep.2025.120908 |
| PMID | 41260550 |
| OpenAlex | W4416400801 |
| Language | EN |
| References cited | 18 |
This study investigated the pharmacodynamics and mechanism of SBPD in treating respiratory inflammation. SBPD protected mice against LPS-induced ALI by alleviating lung tissue damage. Through integrated investigation of the complete formulation and the monomer baicalin, it was collaboratively demonstrated that SBPD exerts anti-inflammatory effects via the NLRP3 inflammasome pathway
Decoction · Inflammasome · Lung · Mechanism (biology · Mechanism of Action · Pharmacodynamics · Signal transduction · Flavonoids in Medical Research · Inflammasome and immune disorders · Medicinal Plants and Bioactive Compounds
| Highly cited | No |
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