A randomized, double-blind, placebo-controlled trial of Wenshenyang decoction for the improvement of renal function and kidney-yang deficiency syndrome in patients with CKD

Bibliographic Data

ID14735346
AuthorsGe Jin (0000-0002-9508-9698, Beijing University of Chinese Medicine), Wenge Li (0000-0002-4749-1009, China-Japan Friendship Hospital), Luying Sun (0000-0003-4847-1410, Beijing University of Chinese Medicine), Baokui Wang (Beijing University of Chinese Medicine), Lanying Liu (0000-0003-2477-4353, Beijing University of Chinese Medicine), Chao Dong (0000-0003-2260-8079, Integrated Chinese Medicine (China)), Tingting Jiao (0009-0008-9785-5959, Capital Medical University), Qi Wu (0000-0001-5487-3278, Beijing University of Chinese Medicine), Yunhua Liu (0000-0001-7210-3381, Beijing University of Chinese Medicine), Xinjiang Zhang (0000-0002-3013-9842, Beijing University of Chinese Medicine), Shuyue Wang (0000-0001-8452-5602, Beijing University of Chinese Medicine), Sitong Wang (0000-0003-3909-5572, Beijing University of Chinese Medicine), Kaidong Zhou (Beijing University of Chinese Medicine), Yanmo Cai (Beijing University of Chinese Medicine), Xin Zhou (0000-0003-2640-6431, Beijing University of Chinese Medicine), Xinxue Zhang (0000-0001-9885-6402, Beijing University of Chinese Medicine), Kun Liu (0009-0004-4829-6776, Beijing University of Chinese Medicine, corresponding author), Zongjiang Zhao (Beijing University of Chinese Medicine, corresponding author)
Year2025
Volume348
Pages119575
Publication date2025-05-01
Peer ReviewedYes
Open AccessYes
TypeARTICLE
VenueJournal of Ethnopharmacology (JOURNAL)
Journal identifiersISSN: 0378-8741 • E-ISSN: 1872-7573
PublisherElsevier BV (PUBLISHER)
DOI10.1016/j.jep.2025.119575
PMID40096899
OpenAlexW4408482539
LanguageEN
Citations received3
References cited19

These results indicate that WSY could improve the renal function and alleviate the kidney Yang deficiency symptoms in patients with CKD without adverse effects. This study provided evidence-based medicine in the treatment of CKD with compound prescriptions of traditional Chinese medicine (TCM) and contributed to promoting the use of phytomedicine

Alternative medicine · Decoction · Double blind · Kidney · Kidney disease · Pathology · Placebo · Randomized controlled trial · Renal function · Traditional medicine · Acupuncture Treatment Research Studies · Healthcare and Venom Research · Medicine · Traditional Chinese Medicine Studies · Internal Medicine

Tools

Open DOIOpen Access