Evidence to support cultivated fruiting body of Ophiocordyceps sinensis (Ascomycota)'s role in relaxing airway smooth muscle

Bibliographic Data

ID14735462
AuthorsHan-Ni Booi (University of Nottingham Malaysia Campus), Li-Yin Pang (University of Nottingham Malaysia Campus), Mei-Kee Lee (0000-0003-4029-1212, University of Nottingham Malaysia Campus), Shin Yee Fung (0000-0002-9288-7328, University of Malaya), Chyan-Leong Ng (National University of Malaysia), Szu-Ting Ng (0000-0002-6023-3063), Chon-Seng Tan, Cin Kong (0000-0002-1970-7394, University of Nottingham Malaysia Campus), Kuan-Hon Lim (0000-0003-1462-3324, University of Nottingham Malaysia Campus), Richard Roberts (0000-0001-9493-0978, University of Nottingham), Kang-Nee Ting (0000-0002-7818-3922, University of Nottingham Malaysia Campus, corresponding author)
Year2025
Volume336
Pages118727
Publication date2025-01-01
Peer ReviewedYes
Open AccessYes
TypeARTICLE
VenueJournal of Ethnopharmacology (JOURNAL)
Journal identifiersISSN: 0378-8741 • E-ISSN: 1872-7573
PublisherElsevier BV (PUBLISHER)
DOI10.1016/j.jep.2024.118727
PMID39182700
OpenAlexW4401853281
LanguageEN
References cited35

These findings suggest that the airway relaxation mechanisms of OCS02® CWE involved cGMP-dependent and cGMP-independent nitric oxide signalling pathways. This study provides evidence that the cultivated strain of OCS02® exhibits airway relaxation effects which supports the traditional use of its wild O. sinensis in strengthening respiratory health

Ascomycota · Biology · Botany · Cordycepin · Cordyceps · Fungus · Gene · Mushroom · Traditional medicine · Chemical synthesis and alkaloids · Fungal Biology and Applications · Herbal Medicine Research Studies · Medicine · Biochemistry