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Heukharang lettuce (Lactuca sativa L.) leaf extract displays sleep-promoting effects through Gabaa receptor

Bibliographic Data

ID14735608
AuthorsYejin Ahn (0000-0002-7016-9798, Korea University), Hee Hwan Lee (STR Biotech (South Korea)), Byung-Hak Kim (STR Biotech (South Korea)), Sang Jae Park (Naver (South Korea)), Young Suk Kim (0000-0003-1343-5647, Ansan University), Hyung Joo Suh (0000-0001-8869-3929, Korea University), Kyungae Jo (0000-0003-4056-6706, Korea University, corresponding author)
Year2023
Volume314
Pages116602
Publication date2023-10-01
Peer ReviewedYes
Open AccessYes
TypeARTICLE
VenueJournal of Ethnopharmacology (JOURNAL)
Journal identifiersISSN: 0378-8741 • E-ISSN: 1872-7573
PublisherElsevier BV (PUBLISHER)
DOI10.1016/j.jep.2023.116602
PMID37149068
OpenAlexW4368367590
LanguageEN
Citations received2
References cited44

HLE increased NREM sleep and significantly improved sleep behavior due to its action on the GABA A receptors. The collective findings suggest that HLE can be used as a novel sleep-enhancing agent in the pharmaceutical and food industries

5-HT receptor · Caffeine · Electroencephalography · GABAA receptor · Hypnotic · Non-rapid eye movement sleep · Receptor · Sedative · Serotonin · Biochemical Analysis and Sensing Techniques · Chemistry · Medicinal Plant Extracts Effects · Medicine · Neuroscience · Psychology · Sleep and Wakefulness Research · Endocrinology · Internal Medicine · Pharmacology

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Unique citing works2
Citations per year2
Citation span2025 - 2025 (1)
Citation velocityrecent
Highly citedNo
Citation typesNeutral: 2

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