Mechanism of the Mongolian medicine Eerdun Wurile basic formula in improving postoperative cognitive dysfunction by inhibiting apoptosis through the Sirt1/p53 signaling pathway

Bibliographic Data

ID14736555
AuthorsYan Li (0000-0001-6650-7726, Inner Mongolia Medical University), Yun Qiao (0000-0003-2970-2594, Inner Mongolia Medical University), Huiru Li (0000-0001-7334-569X, Inner Mongolia Medical University), Zhe Wang (0000-0002-3939-4452, Inner Mongolia Medical University), Enboer Su (Inner Mongolia Medical University), Yiri Du (0000-0002-8465-310X, Inner Mongolia Medical University, corresponding author), Limuge Che (Inner Mongolia Medical University, corresponding author)
Year2023
Volume309
Pages116312
Publication date2023-06-01
Peer ReviewedYes
Open AccessYes
TypeARTICLE
VenueJournal of Ethnopharmacology (JOURNAL)
Journal identifiersISSN: 0378-8741 • E-ISSN: 1872-7573
PublisherElsevier BV (PUBLISHER)
DOI10.1016/j.jep.2023.116312
PMID36863641
OpenAlexW4322625868
LanguageEN
Citations received1
References cited25

EWB can improve POCD with the characteristics of multi-component, multi-target, and multi-pathway synergistic effects. Studies have confirmed that EWB can improve the occurrence of POCD by regulating the expression of genes related to the SIRT1/p53 signal pathway, which provides a new target and basis for the treatment of POCD

Bioinformatics · Biology · Drug · Gene · Gene expression · KEGG · Pathology · Signal transduction · Systems pharmacology · Traditional Chinese medicine · Transcriptome · Anesthesia and Neurotoxicity Research · Intensive Care Unit Cognitive Disorders · Medicine · Neurological Disease Mechanisms and Treatments · Biochemistry · Pharmacology

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