Clerodendrum viscosum leaves attenuate lead-induced neurotoxicity through upregulation of BDNF-Akt-Nrf2 pathway in mice

Bibliographic Data

ID14736626
AuthorsJahidul Islam (0000-0002-5399-8033, University of Rajshahi, corresponding author), Tasnim Tabassum Shila (University of Rajshahi), Zohurul Islam (University of Rajshahi), Ehsanul Kabir (0000-0002-4885-4422, University of Rajshahi), Nazmul Haque (0000-0003-3988-5654, University of Rajshahi), Moriom Khatun (University of Rajshahi), Shuchismita Khan (University of Rajshahi), Ahsanul Mahbub Jubayar (0000-0002-1367-9185, University of Rajshahi), Farhadul Islam (0000-0001-5262-4702, University of Rajshahi), Farjana Nikkon (University of Rajshahi), Khaled Hossain (0000-0003-0878-915X, University of Rajshahi), Zahangir Alam Saud (0000-0003-0019-053X, University of Rajshahi)
Year2023
Volume304
Pages116024
Publication date2023-03-01
Peer ReviewedYes
Open AccessYes
TypeARTICLE
VenueJournal of Ethnopharmacology (JOURNAL)
Journal identifiersISSN: 0378-8741 • E-ISSN: 1872-7573
PublisherElsevier BV (PUBLISHER)
DOI10.1016/j.jep.2022.116024
PMID36549369
OpenAlexW4312084015
LanguageEN
References cited73

This study suggested that C. viscosum leaves restore the cognitive dysfunction and reduce anxiety-like behavior through upregulation of BDNF mediated Akt-Nrf2 pathway in Pb-exposure mice

Antioxidant · Anxiety · Cholinesterase · Downregulation and upregulation · Elevated plus maze · Enzyme · Glutathione · Hippocampus · Morris water navigation task · Neurochemical · Neurotoxicity · Toxicity · Chemistry · Heavy Metal Exposure and Toxicity · Medicinal Plants and Neuroprotection · Medicine · Phytochemicals and Medicinal Plants · Biochemistry · Endocrinology · Internal Medicine · Pharmacology

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