Network pharmacology combined with experimental validation reveals the mechanism of action of cangerzisan on allergic rhinitis

Bibliographic Data

ID14737181
AuthorsFeifan Liu (0000-0003-0881-6365, Yunnan University), Yuanmei Bai (Yunnan University), Xue Wu (0000-0002-9461-3558, Yunnan University), Yan Wan (0000-0003-1840-775X, Yunnan University), Shifang Luo (Yunnan University), Linao Zhang (Yunnan University), Tao Li (0000-0001-7895-4136, Yunnan University), Hua Tang (0000-0002-0177-8864, Yunnan University), Xianjin Tang (0000-0002-7515-2047, Yunnan University), Rong Chen (0009-0009-3347-5065), Qinghua Chen (0000-0001-8226-0006, Yunnan University, corresponding author), Yuhuan Xie (0000-0001-6716-1982, Yunnan University, corresponding author), Peixin Guo (Yunnan University, corresponding author)
Year2024
Volume335
Pages118611
Publication date2024-12-01
Peer ReviewedYes
Open AccessYes
TypeARTICLE
VenueJournal of Ethnopharmacology (JOURNAL)
Journal identifiersISSN: 0378-8741 • E-ISSN: 1872-7573
PublisherElsevier BV (PUBLISHER)
DOI10.1016/j.jep.2024.118611
PMID39053712
OpenAlexW4400927656
LanguageEN
Citations received1
References cited44

The therapeutic mechanism of CEZS against AR involves rectifying TH1/TH2 immune imbalance and upregulating inflammatory and immune factors through modulating key proteins expression within TLR4 pathway. This targeted regulation effectively impedes AR progression

Action (physics · Epistemology · In vitro · Mechanism (biology · Mechanism of Action · Traditional medicine · Allergic Rhinitis and Sensitization · Asthma and respiratory diseases · Chemistry · Dermatology and Skin Diseases · Medicine · Philosophy · Biochemistry · Pharmacology

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