Sishen Wan suppresses colon cancer through dual inhibition of PI3K/AKT/mTOR and STAT3-mitophagy pathways
Network pharmacology and experimental validation
Bibliographic Data
| ID | 14737508 |
|---|---|
| Authors | Chuchu Wang (0000-0002-1851-5534, Chengdu University of Traditional Chinese Medicine), Rongrong Wang (0000-0003-0615-0838, Chengdu University of Traditional Chinese Medicine), Qi Xu (0000-0002-9030-9065, Chengdu University of Traditional Chinese Medicine), Qin Jian (Chengdu University of Traditional Chinese Medicine), Ruli Li (0000-0002-2717-9464, Chengdu University of Traditional Chinese Medicine, corresponding author), Junzhi Lin (0000-0002-5918-5834, Chengdu University of Traditional Chinese Medicine, corresponding author), Chuan Zheng (0000-0002-9181-2383, Chengdu University of Traditional Chinese Medicine, corresponding author) |
| Year | 2026 |
| Volume | 360 |
| Pages | 121039 |
| Publication date | 2026-04-01 |
| Peer Reviewed | Yes |
| Open Access | Yes |
| Type | ARTICLE |
| Venue | Journal of Ethnopharmacology (JOURNAL) |
| Journal identifiers | ISSN: 0378-8741 • E-ISSN: 1872-7573 |
| Publisher | Elsevier BV (PUBLISHER) |
| DOI | 10.1016/j.jep.2025.121039 |
| PMID | 41490553 |
| OpenAlex | W7118077309 |
| Language | EN |
| References cited | 26 |
Autophagy · Cancer · Cell growth · Colorectal cancer · Dual (grammatical number · microRNA · Mitochondrion · Signal transduction · Autophagy in Disease and Therapy · Berberine and alkaloids research · Ginger and Zingiberaceae research
| Citation velocity | historical |
|---|---|
| Highly cited | No |