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Shegan-Mahuang Decoction ameliorates asthmatic airway hyperresponsiveness by downregulating Th2/Th17 cells but upregulating CD4+FoxP3+ Tregs

Bibliographic Data

ID14737517
AuthorsCheng-Chuang Lin (Guangzhou University of Chinese Medicine), Yuan Yuan Wang (0000-0002-2141-4056, Guangzhou University of Chinese Medicine), Yuan-Yuan Wang (0009-0008-7769-8853), Si-Min Chen (Guangzhou University of Chinese Medicine), Yun-Tao Liu, Yuntao Liu (0000-0002-4334-0406, Guangzhou University of Chinese Medicine), Jiqiang Li (0000-0002-7630-9704, Guangzhou University of Chinese Medicine), Ji-Qiang Li, Fang Li (0000-0001-9180-3615, Guangzhou University of Chinese Medicine), Jie-Chen Dai (Guangzhou University of Chinese Medicine), Tong Zhang (0000-0003-1637-0666, Guangzhou University of Chinese Medicine), Feifei Qiu (0000-0002-5073-2125, Guangzhou University of Chinese Medicine), Huazhen Liu (0009-0002-2357-6312, Guangzhou University of Chinese Medicine), Zhenhua Dai (0000-0002-0363-4186, Guangzhou University of Chinese Medicine, corresponding author), Zhong-De Zhang, Zhongde Zhang (0000-0002-8958-3251, Guangzhou University of Chinese Medicine, corresponding author)
Year2020
Volume253
Pages112656
Publication date2020-05-01
Open AccessYes
TypeARTICLE
VenueJournal of Ethnopharmacology (JOURNAL)
Journal identifiersISSN: 0378-8741 • E-ISSN: 1872-7573
PublisherElsevier BV (PUBLISHER)
DOI10.1016/j.jep.2020.112656
PMID32035217
OpenAlexW3005228082
LanguageEN
Citations received9
References cited25

Our findings demonstrate that SMD attenuates asthmatic airway hyperresponsiveness by hindering Th2/Th17 differentiation, promoting CD4+FoxP3+ Treg generation and suppressing mTOR and NF-kB activities

Adenosinergic · Asthma · Biology · Botany · Decoction · FOXP3 · Glycyrrhiza uralensis · Immune system · Receptor · Traditional Chinese medicine · Traditional medicine · Ziziphus jujuba · Asthma and respiratory diseases · Dermatology and Skin Diseases · Immune Cell Function and Interaction · Medicine · Immunology · Internal Medicine · Pharmacology

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Citations per year1.8
Citation span2021 - 2026 (6)
Highly citedNo

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