Experimental validation, molecular docking, proteomic analysis and network pharmacology reveal Morroniside promoting neurogenesis and improving cognitive impairment via Notch1/Hes1 pathway in intracerebroventricular-streptozotocin mice
Bibliographic Data
| ID | 14737853 |
|---|---|
| Authors | Qiwen Tan (0000-0002-2157-7592, Guangzhou University of Chinese Medicine), Zhen Liu (0000-0002-8440-2554, Xiamen University), Jingjing Zheng (0000-0001-6870-4328, Guangzhou University of Chinese Medicine), Yunqian Wang (0000-0003-1587-6913, Guangzhou University of Chinese Medicine), Haitao Wu (0000-0002-5592-7212, Guangzhou University of Chinese Medicine), Qi Wang (0000-0003-0464-2118, Guangzhou University of Chinese Medicine), Yong Liang (0000-0001-5026-6710, Xiamen University, corresponding author) |
| Year | 2025 |
| Volume | 353 |
| Issue | Pt A |
| Pages | 120322 |
| Publication date | 2025-09-01 |
| Peer Reviewed | Yes |
| Open Access | Yes |
| Type | ARTICLE |
| Venue | Journal of Ethnopharmacology (JOURNAL) |
| Journal identifiers | ISSN: 0378-8741 • E-ISSN: 1872-7573 |
| Publisher | Elsevier BV (PUBLISHER) |
| DOI | 10.1016/j.jep.2025.120322 |
| PMID | 40712813 |
| OpenAlex | W4412603163 |
| Language | EN |
| References cited | 53 |
Biology · Cognition · Cognitive impairment · HES1 · Neurogenesis · Notch signaling pathway · Receptor · Axon Guidance and Neuronal Signaling · Epigenetics and DNA Methylation · Medicine · Neurogenesis and neuroplasticity mechanisms · Neuroscience · Internal Medicine · Pharmacology
| Citation velocity | historical |
|---|---|
| Highly cited | No |