Psoralea corylifolia L. seed extract attenuates dexamethasone-induced muscle atrophy in mice by inhibition of oxidative stress and inflammation
Bibliographic Data
| ID | 14738005 |
|---|---|
| Authors | Eunhui Seo (0000-0001-6418-2198, Gachon University), Cao-Sang Truong (0000-0003-2354-5743, Gachon University), Hee-Sook Jun, Hee‐Sook Jun (0000-0002-1166-4932, Gachon University, corresponding author) |
| Year | 2022 |
| Volume | 296 |
| Pages | 115490 |
| Publication date | 2022-10-01 |
| Peer Reviewed | Yes |
| Open Access | Yes |
| Type | ARTICLE |
| Venue | Journal of Ethnopharmacology (JOURNAL) |
| Journal identifiers | ISSN: 0378-8741 • E-ISSN: 1872-7573 |
| Publisher | Elsevier BV (PUBLISHER) |
| DOI | 10.1016/j.jep.2022.115490 |
| PMID | 35728709 |
| OpenAlex | W4283069201 |
| Language | EN |
| Citations received | 4 |
| References cited | 42 |
Here, we demonstrated that PCS extract administration protected against DEX-induced muscle atrophy. This beneficial effect was mediated by suppressing the expression of muscle degradation factors and increasing the expression of muscle regeneration and synthesis factors. This effect was probably due to the inhibition of oxidative stress and inflammation. These results highlight the potential of PCS extract as a protective and therapeutic agent against muscle dysfunction and atrophy
Glutathione peroxidase · Muscle atrophy · Myogenesis · Myogenin · Myosin · Oxidative stress · Pathology · Psoralea corylifolia · Skeletal muscle · Superoxide dismutase · Chemistry · Exercise and Physiological Responses · Medicine · Muscle Physiology and Disorders · Sirtuins and Resveratrol in Medicine · Biochemistry · Endocrinology · Internal Medicine · Pharmacology
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Network pharmacology-based identification of bioavailable anti-inflammatory agents from Psoralea corylifolia L. in an experimental colitis model
| Unique citing works | 4 |
|---|---|
| Citations per year | 1,33 |
| Citation span | 2023 - 2026 (4) |
| Citation velocity | current |
| Highly cited | No |
| Citation types | Neutral: 4 |