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Houshiheisan modulates the NF-κB/MLCK signaling pathway to protect the endothelial barrier in cerebral small vessel disease

Bibliographic Data

ID14738043
AuthorsHong-fa Cheng (Beijing Hospital of Traditional Chinese Medicine), Qiu-yue Yang (Beijing Hospital of Traditional Chinese Medicine), Ya-hui Xie (Beijing Hospital of Traditional Chinese Medicine), Ya-wen Zhang (Beijing Tsinghua Chang Gung Hospital), Qiu-xia Zhang (0000-0001-6751-5699, Beijing Hospital of Traditional Chinese Medicine, corresponding author)
Year2025
Volume344
Pages119502
Publication date2025-03-01
Open AccessYes
TypeARTICLE
VenueJournal of Ethnopharmacology (JOURNAL)
Journal identifiersISSN: 0378-8741 • E-ISSN: 1872-7573
PublisherElsevier BV (PUBLISHER)
DOI10.1016/j.jep.2025.119502
PMID39956300
OpenAlexW4407558846
LanguageEN
Citations received2
References cited46

Biology · Blood–brain barrier · Central nervous system · NF-κB · Signal transduction · Barrier Structure and Function Studies · Chemistry · Medicine · Neuroinflammation and Neurodegeneration Mechanisms · Neurological Disease Mechanisms and Treatments · Cell Biology · Internal Medicine · Pharmacology

  • Houshiheisan Modulates Angiogenic Responses After Ischemic Stroke in Association with miR-126/PIK3R2 and miR-21/Hmga2/WWP1 Signaling

    Open Access•Yu-xiang Wu, Xiao-Yao Guo et al.•Journal of Ethnopharmacology•2026

  • Traditional Chinese medicine as a therapeutic option for cerebral small vessel disease

    Open Access•Xuan Bao, Zexiang Zhang et al.•Journal of Ethnopharmacology•2026

  • Metascape provides a biologist-oriented resource for the analysis of systems-level datasets

    Open Access•Yingyao Zhou, Bin Zhou et al.•Nature Communications•2019

  • Mechanistic insights into Qiteng Xiaozhuo Granules' regulation of autophagy for chronic glomerulonephritis treatment

    Open Access•Tao Liu, Xing Xing Zhuang et al.•Journal of Ethnopharmacology•2024

  • Ginkgolide C attenuates cerebral ischemia/reperfusion-induced inflammatory impairments by suppressing CD40/NF-κB pathway

    Open Access•Bin Li, Baoke Zhang et al.•Journal of Ethnopharmacology•2023

  • BDNF/PI3K/Akt and Nogo-A/RhoA/Rock signaling pathways contribute to neurorestorative effect of Houshiheisan against cerebral ischemia injury in rats

    Open Access•Jiahui Chang, Xiaoquan Yao et al.•Journal of Ethnopharmacology•2016

  • Huzhangqingmaiyin protected vascular endothelial cells against cerebral small vessel disease through inhibiting inflammation

    Open Access•Meng-Ting Li, Jia Ke et al.•Journal of Ethnopharmacology•2024

Citations per year2
Citation span2026 - 2026 (1)
Highly citedNo

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