Integrating metabolomics, network pharmacology and pharmacological verification analysis provides new insights into the anti-inflammatory and anti-tussive properties of Fritillaria cirrhosa bulbs

Bibliographic Data

ID14738513
AuthorsCan Zhao (0000-0003-2499-222X, Chengdu University of Traditional Chinese Medicine), Jianyun Zhang (0000-0002-8649-9601, Chengdu University of Traditional Chinese Medicine), Zhihuang Zhao (0009-0006-0539-0468, Guiyang College of Traditional Chinese Medicine), Xueyan Li (0009-0002-2230-6468, Chengdu University of Traditional Chinese Medicine), Xin Chen (0000-0001-7221-0056, Chengdu University of Traditional Chinese Medicine), Hai Wang (0000-0002-9260-3428, Chengdu University of Traditional Chinese Medicine), Yuntong Ma (0000-0001-6554-5317, Chengdu University of Traditional Chinese Medicine), Guiqi Han (Chengdu University of Traditional Chinese Medicine, corresponding author), Zhuyun Yan (0000-0003-2501-3652, Chengdu University of Traditional Chinese Medicine, corresponding author)
Year2025
Volume343
Pages119460
Publication date2025-03-01
Peer ReviewedYes
Open AccessYes
TypeARTICLE
VenueJournal of Ethnopharmacology (JOURNAL)
Journal identifiersISSN: 0378-8741 • E-ISSN: 1872-7573
PublisherElsevier BV (PUBLISHER)
DOI10.1016/j.jep.2025.119460
PMID39952421
OpenAlexW4407393406
LanguageEN
Citations received1
References cited35

By integrating metabolomic and network analyses, the traditional classification of F. cirrhosa into SB and QB based on bulb characteristics and the observed differences are justified to a certain extent. This study provides new insights, guiding the clinical use of these treatments for inflammation and cough

Anti-inflammatory · Biological activity · Biology · Drug · In vitro · Pharmacognosy · Systems pharmacology · Traditional medicine · Chromatography in Natural Products · Medicine · Natural product bioactivities and synthesis · Phytochemical Studies and Bioactivities · Biochemistry · Pharmacology

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