The active components and potential mechanisms of Li-Chong-Xiao-Zhen granules in the treatment of ovarian cancer
An integrated metabolomics, proteomics, network pharmacology and experimental validation
Bibliographic Data
| ID | 14738583 |
|---|---|
| Authors | Yiliu Chen (0000-0003-0309-1510, Jinan University), Ran Su, Rina Su (0000-0001-7975-3280, Jinan University), Yunguang Hu, Guilin Hu (0009-0001-6404-9968, Jinan University), Jiali Luo (0000-0002-6638-8971, Jinan University), Chu Yi (Jinan University), Yuanfang Zhu (0000-0003-0980-9829, Jinan University), Yinbin Zhu, Qing Feng (0009-0002-1206-1807, Jinan University), Xianxin Yan (Jinan University, corresponding author), Min Ma (0000-0002-6652-7214), Ma Min (0000-0001-5236-1295), Weifeng Feng (0000-0002-1929-6484, First Affiliated Hospital of Jinan University, corresponding author) |
| Year | 2025 |
| Volume | 343 |
| Pages | 119474 |
| Publication date | 2025-03-01 |
| Peer Reviewed | Yes |
| Open Access | Yes |
| Type | ARTICLE |
| Venue | Journal of Ethnopharmacology (JOURNAL) |
| Journal identifiers | ISSN: 0378-8741 • E-ISSN: 1872-7573 |
| Publisher | Elsevier BV (PUBLISHER) |
| DOI | 10.1016/j.jep.2025.119474 |
| PMID | 39938763 |
| OpenAlex | W4407302480 |
| Language | EN |
| Citations received | 1 |
| References cited | 41 |
This study demonstrated that most of the active Compound of LCXZG are Paeoniflorin, Turanose, Amygdalin and Benzoylpaeoniflorin, which may exert their anti-tumor effects by regulating glycerophospholipid metabolism in ovarian cancer
Active compound · Bioinformatics · Biology · Cancer · Metabolomics · Ovarian cancer · Proteomics · Stereochemistry · Traditional medicine · Cancer, Lipids, and Metabolism · Chemistry · Medicine · Metabolomics and Mass Spectrometry Studies · Natural product bioactivities and synthesis · Biochemistry · Internal Medicine · Pharmacology
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Integrated proteomic and metabolomic analysis reveals the potential therapeutic mechanism of Quanduzhong capsule in rats with spontaneous hypertension and knee osteoarthritis
| Unique citing works | 1 |
|---|---|
| Citations per year | 1 |
| Citation span | 2026 - 2026 (1) |
| Citation velocity | current |
| Highly cited | No |
| Citation types | Neutral: 1 |