Protective effects of Angelica decursiva Franchet & Savatier on allergic responses through enhancement of Nrf2 and suppression of NF-kB/MMP-9 in ovalbumin-exposed mice

Bibliographic Data

ID14738752
AuthorsSe-Jin Lee (0000-0001-9577-4305), Se‐Jin Lee (0000-0001-9391-0086, Chonnam National University), A Yeong Lee (0000-0003-1670-8911, Korea Institute of Oriental Medicine), So-Won Pak, So‐Won Pak (0000-0003-1629-750X, Chonnam National University), Woong-Il Kim, Woong‐Il Kim (0000-0002-3308-0313, Chonnam National University), Yea-Gin Yang (Chonnam National University), Je-Oh Lim, Je‐Oh Lim (0000-0002-0648-8348, Korea Institute of Oriental Medicine), Sungwook Chae (0000-0001-9789-0043, Korea Institute of Oriental Medicine), Sung-wook Chae, Young-Kwon Cho (0000-0003-2293-5141, Cheongju University), Jong-Choon Kim (0000-0002-8265-9911, Chonnam National University), Byeong Cheol Moon (0000-0002-5374-6274, Korea Institute of Oriental Medicine), Yun-Soo Seo (0000-0003-4414-3495, Korea Institute of Oriental Medicine, corresponding author), In-Sik Shin (0000-0002-7343-426X, Chonnam National University, corresponding author)
Year2024
Volume318
IssuePt A
Pages116863
Publication date2024-01-01
Peer ReviewedYes
Open AccessYes
TypeARTICLE
VenueJournal of Ethnopharmacology (JOURNAL)
Journal identifiersISSN: 0378-8741 • E-ISSN: 1872-7573
PublisherElsevier BV (PUBLISHER)
DOI10.1016/j.jep.2023.116863
PMID37423516
OpenAlexW4383558811
LanguageEN
References cited34

This study demonstrated that ADE effectively attenuated allergic inflammation induced by OVA inhalation through the enhancement of Nrf2 expression and suppression of NF-κB expression. Therefore, ADE may be a potential therapeutic agent for controlling asthma

Asthma · Bronchoalveolar lavage · Immune system · Intraperitoneal injection · Lipopolysaccharide · Lung · Ovalbumin · Asthma and respiratory diseases · Genomics, phytochemicals, and oxidative stress · Medicine · Plant chemical constituents analysis · Immunology · Internal Medicine · Pharmacology

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