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Integrated activity-guided isolation and transcriptomic analysis reveal the therapeutic mechanism of Thonningianin A from Penthhorum chinense Pursh against colorectal cancer via p21 modulation

Bibliographic Data

ID14739001
AuthorsFanmuchen Zeng (Jiangxi Normal University), Zeng Fan (0009-0008-6549-2823, Jiangxi Normal University), Xuan Jiang (0000-0001-7802-0165, Dalian Institute of Chemical Physics), Fengmin Xiong (Shanghai Innovative Research Center of Traditional Chinese Medicine), Siyu Yao (0000-0002-9673-6404, Jiangxi Normal University), Wenying Lu (0000-0003-1550-2276, Shanghai Innovative Research Center of Traditional Chinese Medicine), Yingli Chen (0000-0003-0937-3375, Shanghai Innovative Research Center of Traditional Chinese Medicine), Huilin Yang (0000-0003-4483-5109, Jiangxi Normal University, corresponding author), Xianlong Ye (Shanghai Innovative Research Center of Traditional Chinese Medicine, corresponding author)
Year2026
Volume355
IssuePt A
Pages120655
Publication date2026-01-01
Open AccessYes
TypeARTICLE
VenueJournal of Ethnopharmacology (JOURNAL)
Journal identifiersISSN: 0378-8741 • E-ISSN: 1872-7573
PublisherElsevier BV (PUBLISHER)
DOI10.1016/j.jep.2025.120655
PMID41016541
OpenAlexW4414624884
LanguageEN
References cited40

Blockade · Cancer · Cell culture · Colorectal cancer · Isolation (microbiology · Mechanism (biology · Mechanism of Action · Transcriptome · Bioactive natural compounds · Natural product bioactivities and synthesis · Phytochemical Studies and Bioactivities · Phytochemistry and Bioactive Compounds · Phytochemistry and Biological Activities

  • A review of Penthorum chinense Pursh for hepatoprotection

    Open Access•Anqi Wang, Mingxing Li et al.•Journal of Ethnopharmacology•2020

Highly citedNo

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