The Codonopsis pilosula water extract improves testicular inflammatory aging in D-galactose induced aging mice by modulating the CLEC7A/inflammasome pathway
Bibliographic Data
| ID | 14739196 |
|---|---|
| Authors | Jing Wang (0000-0002-7594-8539, Gansu University of Traditional Chinese Medicine), Xuechan Li (Gansu University of Traditional Chinese Medicine), Caihong Li (0000-0002-2256-1971, Gansu University of Traditional Chinese Medicine), Lijun Liu (0000-0002-8628-255X, First Hospital of Lanzhou University), Zhenjuan Wang (Gansu University of Traditional Chinese Medicine), Juan Feng (0000-0002-3229-5582, Shenzhen Technology University, corresponding author) |
| Year | 2025 |
| Volume | 346 |
| Pages | 119645 |
| Publication date | 2025-04-01 |
| Peer Reviewed | Yes |
| Open Access | Yes |
| Type | ARTICLE |
| Venue | Journal of Ethnopharmacology (JOURNAL) |
| Journal identifiers | ISSN: 0378-8741 • E-ISSN: 1872-7573 |
| Publisher | Elsevier BV (PUBLISHER) |
| DOI | 10.1016/j.jep.2025.119645 |
| PMID | 40113110 |
| OpenAlex | W4408567053 |
| Language | EN |
| References cited | 40 |
Biological activity · Biology · Galactose · In vitro · Inflammasome · Inflammation · Pharmacognosy · Traditional medicine · Antioxidants, Aging, Portulaca oleracea · Chemistry · Diet, Metabolism, and Disease · Medicinal Plants and Bioactive Compounds · Medicine · Biochemistry · Immunology · Pharmacology
Dose translation from animal to human studies revisited
Effects and mechanism of extracts rich in phenylpropanoids-polyacetylenes and polysaccharides from Codonopsis Radix on improving scopolamine-induced memory impairment of mice
Codonopsis pilosula water extract delays D-galactose-induced aging of the brain in mice by activating autophagy and regulating metabolism
Multi-omics revealed the mechanisms of Codonopsis pilosula aqueous extract in improving UC through blocking abnormal activation of PI3K/Akt signaling pathway
| Citation velocity | historical |
|---|---|
| Highly cited | No |