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Protective effect of liquiritin against cisplatin-induced liver injury in mice through reduction of inflammation, oxidative stress, apoptosis and inhibition of p38 Mapk/p53 pathway based on network pharmacology and in experimental validation

Datos Bibliográficos

ID14739617
AutoresQiuxiang Wang (0000-0002-4657-5331, Hebei Medical University), Mengqi Xian (Hebei University of Chinese Medicine), Ming Xian (0000-0002-7902-2987, Hebei University of Chinese Medicine), Chen Li (0000-0001-6150-8594), Li Chen (0000-0002-8432-3338, Hebei University of Chinese Medicine), Lili Mi (0000-0002-4044-1439, Hebei Medical University), Junwei Ji (0000-0001-6996-990X, Hebei Medical University), Zhonglin Wu (Hebei Medical University), Xuelian Shi (Hebei Medical University), Xue Han (0000-0002-1156-4077, Hebei University of Chinese Medicine)
Año2026
Volumen354
Páginas120536
Fecha de publicación2026-01-01
Peer ReviewedSí
Open AccessSí
TipoARTICLE
RevistaJournal of Ethnopharmacology (JOURNAL)
Identificadores de la revistaISSN: 0378-8741 • E-ISSN: 1872-7573
EditorialElsevier BV (PUBLISHER)
DOI10.1016/j.jep.2025.120536
PMID40912484
OpenAlexW4413947977
IdiomaEN
Referencias citadas70

Apoptosis · Chemotherapy · Cisplatin · Inflammation · Liver injury · MAPK/ERK pathway · Oxidative stress · p38 mitogen-activated protein kinases · Pathology · Signal transduction · Traditional Chinese medicine · Biochemistry · Chemistry · Chemotherapy-induced organ toxicity mitigation · Drug-Induced Hepatotoxicity and Protection · Endocrinology · Immunology · Internal Medicine · Medicine · Pharmacological Effects of Natural Compounds · Pharmacology

  • A bibliometric review of Glycyrrhizae Radix et Rhizoma (licorice) research

    Open Access•Yushan Zhang, Jing Lü et al.•Journal of Ethnopharmacology•2024

  • Pharmacodynamic material basis of licorice and mechanisms of modulating bile acid metabolism and gut microbiota in cisplatin-induced liver injury based on LC-MS and network pharmacology analysis

    Open Access•Jie Li, Xiaolong Lian et al.•Journal of Ethnopharmacology•2025

  • Investigation of the principle of concoction by using the processing excipient Glycyrrhiza uralensis Fisch. juice to reduce the main toxicity of Dioscorea bulbifera L. and enhance its main efficacy as expectorant and cough suppressant

    Open Access•Lingling Song, Junming Wang et al.•Journal of Ethnopharmacology•2024

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