Integrated serum pharmacochemistry and network pharmacology analyses reveal the bioactive metabolites and potential functional mechanism of ground cherry (Physalis pruinosa L.) in treatment of type 2 diabetes mellitus in rats
Bibliographic Data
| ID | 14739655 |
|---|---|
| Authors | Asmaa Mahana (Alexandria University), Hala M Hammoda (0000-0002-9484-1761, Alexandria University), Asmaa A Khalifa (0000-0003-2507-3188, Pharos University in Alexandria), Samar S Elblehi (0000-0003-4939-1754, Alexandria University), Fathallah M Harraz (Alexandria University), Eman Shawky (0000-0003-0089-9629, Alexandria University, corresponding author) |
| Year | 2023 |
| Volume | 300 |
| Pages | 115750 |
| Publication date | 2023-01-01 |
| Peer Reviewed | Yes |
| Open Access | Yes |
| Type | ARTICLE |
| Venue | Journal of Ethnopharmacology (JOURNAL) |
| Journal identifiers | ISSN: 0378-8741 • E-ISSN: 1872-7573 |
| Publisher | Elsevier BV (PUBLISHER) |
| DOI | 10.1016/j.jep.2022.115750 |
| PMID | 36162547 |
| OpenAlex | W4297181174 |
| Language | EN |
| Citations received | 1 |
| References cited | 27 |
The study in hand offers a comprehensive study to clarify the bioactive metabolites of the different organs of P. pruinosa. The basic pharmacological effects and underlying mechanism of actions in the management of STZ and high fat diet induced T2DM were specifically covered in this paper
Biology · Diabetes mellitus · Gene · Gene expression · Gene ontology · In vitro · In vivo · KEGG · Mechanism of Action · Physalis · Streptozotocin · Traditional medicine · Type 2 diabetes · Type 2 Diabetes Mellitus · Chemistry · Computational Drug Discovery Methods · Medicine · Natural Antidiabetic Agents Studies · Phytochemicals and Medicinal Plants · Biochemistry · Biotechnology · Endocrinology · Pharmacology
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Antidiabetic potential of the ethyl acetate extract of Physalis alkekengi and chemical constituents identified by HPLC-ESI-QTOF-MS
| Unique citing works | 1 |
|---|---|
| Citations per year | 0,5 |
| Citation span | 2024 - 2024 (1) |
| Citation velocity | recent |
| Highly cited | No |
| Citation types | Neutral: 1 |