Duhuo Jisheng decoction alleviates intervertebral disc degeneration by inhibiting nucleus pulposus cell pyroptosis via gallic acid-mediated downregulation of HIF-1α
Bibliographic Data
| ID | 14739720 |
|---|---|
| Authors | Junjie Cheng (0009-0000-6455-975X, Zhujiang Hospital), Jianjun Li (0000-0003-2872-9648, Zhujiang Hospital), Cheng Yu (0000-0002-3535-0567, Third Affiliated Hospital of Southern Medical University), Wenhao Kuang (Zhujiang Hospital), Runjun Luo (Dongguan People’s Hospital), Rongze Luo (0000-0002-8131-8277, Dongguan People’s Hospital), Zhihui Zhou (0000-0001-7254-8786, Dongguan People’s Hospital), Jianfeng Zhang (0000-0003-2596-5143, Dongguan People’s Hospital), Yang Duan (0000-0002-6084-1026, Zhujiang Hospital, corresponding author) |
| Year | 2026 |
| Volume | 358 |
| Pages | 120957 |
| Publication date | 2026-03-01 |
| Peer Reviewed | Yes |
| Open Access | Yes |
| Type | ARTICLE |
| Venue | Journal of Ethnopharmacology (JOURNAL) |
| Journal identifiers | ISSN: 0378-8741 • E-ISSN: 1872-7573 |
| Publisher | Elsevier BV (PUBLISHER) |
| DOI | 10.1016/j.jep.2025.120957 |
| PMID | 41317810 |
| OpenAlex | W4416757935 |
| Language | EN |
| References cited | 41 |
Apoptosis · Cell · Downregulation and upregulation · Gallic acid · Oxidative stress · Paeoniflorin · Programmed cell death · Pyroptosis · Gout, Hyperuricemia, Uric Acid · Spine and Intervertebral Disc Pathology · Spondyloarthritis Studies and Treatments
ClusterProfiler
Intervertebral disc degeneration—Current therapeutic options and challenges
Duhuo jisheng decoction suppresses matrix degradation and apoptosis in human nucleus pulposus cells and ameliorates disc degeneration in a rat model
The effects of Jiawei Duhuo Jisheng mixture on Wnt/β-catenin signaling pathway in the synovium inflamed by knee osteoarthritis
| Citation velocity | historical |
|---|---|
| Highly cited | No |