Integrating network pharmacology and metabolomics to explore the mechanism of Xihuang Pill in exerting anti-tumor immune effects against pancreatic ductal adenocarcinoma
Bibliographic Data
| ID | 14740241 |
|---|---|
| Authors | Zhiqiao Wang (0000-0002-9716-5885, Sichuan Academy of Traditional Chinese Medicine), Xuerong Zhou, Xue‐Rong Zhou (0000-0003-3717-2984, Sichuan Academy of Traditional Chinese Medicine), Yanlei Guo (0000-0003-2913-0530, Chongqing Academy of Chinese Materia Medica), Jinmei Zhang (0000-0002-3824-8496, Sichuan Academy of Traditional Chinese Medicine), Yaou Liu (0000-0002-9930-0331, Sichuan Academy of Traditional Chinese Medicine), Jin Zeng (0000-0003-1297-3734, Sichuan Academy of Traditional Chinese Medicine, corresponding author), Junning Zhao (0009-0008-9190-1619, Sichuan Academy of Traditional Chinese Medicine, corresponding author) |
| Year | 2026 |
| Volume | 356 |
| Pages | 120788 |
| Publication date | 2026-02-01 |
| Peer Reviewed | Yes |
| Open Access | Yes |
| Type | ARTICLE |
| Venue | Journal of Ethnopharmacology (JOURNAL) |
| Journal identifiers | ISSN: 0378-8741 • E-ISSN: 1872-7573 |
| Publisher | Elsevier BV (PUBLISHER) |
| DOI | 10.1016/j.jep.2025.120788 |
| PMID | 41161625 |
| OpenAlex | W4415595454 |
| Language | EN |
| References cited | 33 |
Immune system · Mechanism (biology · Metabolite · Metabolomics · Pancreatic cancer · Pancreatic ductal adenocarcinoma · Pill · Signal transduction · Tumor microenvironment · Ferroptosis and cancer prognosis · Ginseng Biological Effects and Applications · Immune cells in cancer · Metabolomics and Mass Spectrometry Studies · Pharmacological Effects of Natural Compounds · Tryptophan and brain disorders
A new discovery
The mechanism of Xihuang pills' intervention in the tumour immune microenvironment for the treatment of liver cancer based on the STAT3-PDL1 pathway
Qingyihuaji Formula promotes apoptosis and autophagy through inhibition of Mapk/ERK and PI3K/Akt/mTOR signaling pathway on pancreatic cancer in vivo and in vitro
| Citation velocity | historical |
|---|---|
| Highly cited | No |