Baihe Wuyao decoction ameliorates CCl4-induced chronic liver injury and liver fibrosis in mice through blocking TGF-β1/Smad2/3 signaling, anti-inflammation and anti-oxidation effects

Bibliographic Data

ID14740343
AuthorsYajing Chen (0000-0002-0362-7138, North China University of Science and Technology), Ruofei Li (North China University of Science and Technology), Nan Hu (0000-0003-4866-4263, North China University of Science and Technology), Chunping Yu (0000-0003-2310-3777, North China University of Science and Technology), Hongyu Song (0009-0009-7608-8735, North China University of Science and Technology), Yida Li (0000-0001-5973-8278, North China University of Science and Technology), Yujiao Dai (0000-0003-0437-4002, North China University of Science and Technology), Zhao Guo (0000-0003-1477-0842, North China University of Science and Technology), Meng Li (0000-0003-4257-1832, North China University of Science and Technology), Yi Zheng (0000-0002-2228-2948, North China University of Science and Technology), Zhiyi Guo (0009-0006-0836-1929, North China University of Science and Technology), Yajuan Qi (0000-0002-4078-786X, North China University of Science and Technology, corresponding author)
Year2020
Volume263
Pages113227
Publication date2020-12-01
Peer ReviewedYes
Open AccessYes
TypeARTICLE
VenueJournal of Ethnopharmacology (JOURNAL)
Journal identifiersISSN: 0378-8741 • E-ISSN: 1872-7573
PublisherElsevier BV (PUBLISHER)
DOI10.1016/j.jep.2020.113227
PMID32783983
OpenAlexW3047645419
LanguageEN
Citations received4
References cited34

BWD ameliorates CCl 4 -induced CLI and liver fibrosis which is correlated to its blocking TGF-β1/Smad2/3 signaling, anti-inflammation, and anti-oxidation effects. BWD, as a small traditional prescription, is a promising treatment for CLI and liver fibrosis through multiple pharmacological targets

Alanine transaminase · Carbon tetrachloride · Fibrosis · H&E stain · Hepatic fibrosis · Intraperitoneal injection · Liver injury · Pathology · Sirius Red · Staining · Chemistry · Drug-Induced Hepatotoxicity and Protection · Liver Disease Diagnosis and Treatment · Liver physiology and pathology · Medicine · Internal Medicine · Pharmacology

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