In silico analysis of the potential mechanism of a preventive Chinese medicine formula on coronavirus disease 2019

Datos Bibliográficos

ID14740672
AutoresHuaying Wu (Hunan University of Traditional Chinese Medicine), Ke Gong (0000-0003-0202-8747), You Qin (0000-0002-6582-1526, Hunan Academy of Traditional Chinese Medicine), Zhiying Yuan (0000-0002-3072-4515, Hunan University of Traditional Chinese Medicine), Shuaishuai Xia (Hunan University), Shiying Zhang (0009-0003-6009-4563, Shenzhen Luohu People's Hospital), Jingjing Yang (0000-0003-1427-3117), Ping Yang (0000-0002-3646-438X, Hunan Institute of Mental Health), Liang Li (0000-0002-1688-1143, Hunan University, autor de correspondencia), Mengzhou Xie (0000-0002-4896-1797, Hunan University, autor de correspondencia)
Año2021
Volumen275
Páginas114098
Fecha de publicación2021-07-01
Peer ReviewedSí
Open AccessSí
TipoARTICLE
RevistaJournal of Ethnopharmacology (JOURNAL)
Identificadores de la revistaISSN: 0378-8741 • E-ISSN: 1872-7573
EditorialElsevier BV (PUBLISHER)
DOI10.1016/j.jep.2021.114098
PMID33831468
OpenAlexW3145381471
IdiomaEN
Citas recibidas1
Referencias citadas48

The present study showed that XG-1 exerts a preventive effect in close contacts against COVID-19. The underlying mechanism may be related to modulate immunity response through multiple components, pathways, and several target genes co-expressed with ACE2. These findings provide preliminary evidences and methodological reference for the potential preventive mechanism of XG-1 against COVID-19

Alternative medicine · Biology · Computational biology · Drug · Gene · Gene expression · Gene expression profiling · Gene ontology · KEGG · Systems pharmacology · Traditional Chinese medicine · Traditional medicine · Long-Term Effects of COVID-19 · Medicinal Plants and Bioactive Compounds · Medicine · Tryptophan and brain disorders · Genetics · Pharmacology